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1gav

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(New page: 200px<br /><applet load="1gav" size="450" color="white" frame="true" align="right" spinBox="true" caption="1gav, resolution 3.4&Aring;" /> '''BACTERIOPHAGE GA PROT...)
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[[Image:1gav.gif|left|200px]]<br /><applet load="1gav" size="450" color="white" frame="true" align="right" spinBox="true"
 
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caption="1gav, resolution 3.4&Aring;" />
 
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'''BACTERIOPHAGE GA PROTEIN CAPSID'''<br />
 
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==Overview==
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==BACTERIOPHAGE GA PROTEIN CAPSID==
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The three-dimensional structure of the small T=3 RNA bacteriophage GA has, been determined at 3.4 A resolution. The structure was solved by molecular, replacement, using the phage MS2 as an initial model. A comparison of the, protein shells of the four related phages GA, MS2, fr and Qbeta was, carried out in order to define structural features of particular, importance for their assembly and specific RNA interaction. A high degree, of similarity was found in the RNA binding sites, whereas larger, structural differences are located in the loop regions of the coat, proteins, especially in the FG loops forming 5-fold and quasi-6-fold, contacts. The overall arrangement of the protein subunits in the shells of, these phages is very similar, although the details of the interactions, differ. The few conserved interactions are suggested to govern the subunit, packing during assembly.
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<StructureSection load='1gav' size='340' side='right'caption='[[1gav]], [[Resolution|resolution]] 3.40&Aring;' scene=''>
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== Structural highlights ==
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==About this Structure==
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<table><tr><td colspan='2'>[[1gav]] is a 45 chain structure with sequence from [https://en.wikipedia.org/wiki/Enterobacteria_phage_GA Enterobacteria phage GA]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GAV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1GAV FirstGlance]. <br>
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1GAV is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Vibrio_phage_ch457 Vibrio phage ch457]. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1GAV OCA].
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.4&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1gav FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1gav OCA], [https://pdbe.org/1gav PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1gav RCSB], [https://www.ebi.ac.uk/pdbsum/1gav PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1gav ProSAT]</span></td></tr>
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==Reference==
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</table>
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The crystal structure of bacteriophage GA and a comparison of bacteriophages belonging to the major groups of Escherichia coli leviviruses., Tars K, Bundule M, Fridborg K, Liljas L, J Mol Biol. 1997 Sep 5;271(5):759-73. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=9299325 9299325]
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== Function ==
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[[Category: Single protein]]
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[https://www.uniprot.org/uniprot/CAPSD_BPGA CAPSD_BPGA] Capsid protein self-assembles to form an icosahedral capsid with a T=3 symmetry, about 26 nm in diameter, and consisting of 89 capsid proteins dimers (178 capsid proteins). Involved in viral genome encapsidation through the interaction between a capsid protein dimer and the multiple packaging signals present in the RNA genome. The capsid contains also 1 copy of the A2 maturation protein.[UniProtKB:P03612] Acts as a translational repressor of viral replicase synthesis late in infection. This latter function is the result of capsid protein interaction with an RNA hairpin which contains the replicase ribosome-binding site.[UniProtKB:P03612]
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[[Category: Vibrio phage ch457]]
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__TOC__
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[[Category: Bundule, M.]]
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</StructureSection>
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[[Category: Liljas, L.]]
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[[Category: Enterobacteria phage GA]]
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[[Category: Tars, K.]]
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[[Category: Large Structures]]
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[[Category: bacteriophage]]
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[[Category: Bundule M]]
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[[Category: capsid]]
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[[Category: Liljas L]]
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[[Category: coat protein]]
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[[Category: Tars K]]
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[[Category: icosahedral virus]]
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''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Nov 20 15:53:28 2007''
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Current revision

BACTERIOPHAGE GA PROTEIN CAPSID

PDB ID 1gav

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