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1gnw

From Proteopedia

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[[Image:1gnw.png|left|200px]]
 
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{{STRUCTURE_1gnw| PDB=1gnw | SCENE= }}
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==STRUCTURE OF GLUTATHIONE S-TRANSFERASE==
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<StructureSection load='1gnw' size='340' side='right'caption='[[1gnw]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1gnw]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GNW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1GNW FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GTX:S-HEXYLGLUTATHIONE'>GTX</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1gnw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1gnw OCA], [https://pdbe.org/1gnw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1gnw RCSB], [https://www.ebi.ac.uk/pdbsum/1gnw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1gnw ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/GSTF2_ARATH GSTF2_ARATH] Binds auxin, endogenous flavonoids and the phytoalexin camalexin and may be involved in regulating the binding and transport of small bioactive natural products and defense-related compounds during plant stress. Binds a series of heterocyclic compounds, including lumichrome, harmane, norharmane and indole-3-aldehyde. In vitro, possesses glutathione S-transferase activity toward 1-chloro-2,4-dinitrobenzene (CDNB) and benzyl isothiocyanate (BITC). Acts as glutathione peroxidase on cumene hydroperoxide, linoleic acid-13-hydroperoxide and trans-stilbene oxide, but not trans-cinnamic acid or IAA-CoA.<ref>PMID:12090627</ref> <ref>PMID:21631432</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gn/1gnw_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1gnw ConSurf].
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<div style="clear:both"></div>
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===STRUCTURE OF GLUTATHIONE S-TRANSFERASE===
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==See Also==
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*[[Glutathione S-transferase 3D structures|Glutathione S-transferase 3D structures]]
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{{ABSTRACT_PUBMED_8551521}}
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== References ==
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<references/>
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==About this Structure==
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__TOC__
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[[1gnw]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GNW OCA].
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</StructureSection>
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==Reference==
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<ref group="xtra">PMID:008551521</ref><references group="xtra"/>
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[[Category: Arabidopsis thaliana]]
[[Category: Arabidopsis thaliana]]
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[[Category: Glutathione transferase]]
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[[Category: Large Structures]]
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[[Category: Bartunik, H D.]]
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[[Category: Bartunik HD]]
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[[Category: Bieseler, B.]]
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[[Category: Bieseler B]]
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[[Category: Hof, P.]]
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[[Category: Hof P]]
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[[Category: Huber, R.]]
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[[Category: Huber R]]
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[[Category: Neuefeind, T.]]
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[[Category: Neuefeind T]]
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[[Category: Palme, K.]]
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[[Category: Palme K]]
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[[Category: Prade, L.]]
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[[Category: Prade L]]
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[[Category: Reinemer, P.]]
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[[Category: Reinemer P]]
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[[Category: Herbicide detoxification]]
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[[Category: Transferase]]
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Current revision

STRUCTURE OF GLUTATHIONE S-TRANSFERASE

PDB ID 1gnw

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