This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1hlv

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
m (Protected "1hlv" [edit=sysop:move=sysop])
Current revision (07:28, 7 February 2024) (edit) (undo)
 
(7 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:1hlv.png|left|200px]]
 
-
{{STRUCTURE_1hlv| PDB=1hlv | SCENE= }}
+
==CRYSTAL STRUCTURE OF CENP-B(1-129) COMPLEXED WITH THE CENP-B BOX DNA==
 +
<StructureSection load='1hlv' size='340' side='right'caption='[[1hlv]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
 +
== Structural highlights ==
 +
<table><tr><td colspan='2'>[[1hlv]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HLV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1HLV FirstGlance]. <br>
 +
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
 +
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1hlv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hlv OCA], [https://pdbe.org/1hlv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1hlv RCSB], [https://www.ebi.ac.uk/pdbsum/1hlv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1hlv ProSAT], [https://www.topsan.org/Proteins/RSGI/1hlv TOPSAN]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/CENPB_HUMAN CENPB_HUMAN] Interacts with centromeric heterochromatin in chromosomes and binds to a specific subset of alphoid satellite DNA, called the CENP-B box. May organize arrays of centromere satellite DNA into a higher-order structure which then directs centromere formation and kinetochore assembly in mammalian chromosomes.
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hl/1hlv_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1hlv ConSurf].
 +
<div style="clear:both"></div>
-
===CRYSTAL STRUCTURE OF CENP-B(1-129) COMPLEXED WITH THE CENP-B BOX DNA===
+
==See Also==
-
 
+
*[[Centromere protein 3D structure|Centromere protein 3D structure]]
-
{{ABSTRACT_PUBMED_11726497}}
+
__TOC__
-
 
+
</StructureSection>
-
==About this Structure==
+
-
[[1hlv]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HLV OCA].
+
-
 
+
-
==Reference==
+
-
<ref group="xtra">PMID:011726497</ref><references group="xtra"/>
+
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
-
[[Category: Fukai, S.]]
+
[[Category: Large Structures]]
-
[[Category: Ikuta, M.]]
+
[[Category: Fukai S]]
-
[[Category: Iwahara, J.]]
+
[[Category: Ikuta M]]
-
[[Category: Kawaguchi, S.]]
+
[[Category: Iwahara J]]
-
[[Category: Kurumizaka, H.]]
+
[[Category: Kawaguchi S]]
-
[[Category: Nureki, O.]]
+
[[Category: Kurumizaka H]]
-
[[Category: Okazaki, T.]]
+
[[Category: Nureki O]]
-
[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
+
[[Category: Okazaki T]]
-
[[Category: Tanaka, Y.]]
+
[[Category: Tanaka Y]]
-
[[Category: Yokoyama, S.]]
+
[[Category: Yokoyama S]]
-
[[Category: Dna binding protein-dna complex]]
+
-
[[Category: Helix-turn-helix]]
+
-
[[Category: Protein-dna complex]]
+
-
[[Category: Riken structural genomics/proteomics initiative]]
+
-
[[Category: Rsgi]]
+
-
[[Category: Structural genomic]]
+

Current revision

CRYSTAL STRUCTURE OF CENP-B(1-129) COMPLEXED WITH THE CENP-B BOX DNA

PDB ID 1hlv

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1hlv"
Personal tools