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1i3j

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{{Seed}}
 
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[[Image:1i3j.png|left|200px]]
 
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==CRYSTAL STRUCTURE OF THE DNA-BINDING DOMAIN OF INTRON ENDONUCLEASE I-TEVI WITH ITS SUBSTRATE==
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The line below this paragraph, containing "STRUCTURE_1i3j", creates the "Structure Box" on the page.
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<StructureSection load='1i3j' size='340' side='right'caption='[[1i3j]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1i3j]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_virus_T4 Escherichia virus T4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1I3J OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1I3J FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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{{STRUCTURE_1i3j| PDB=1i3j | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1i3j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1i3j OCA], [https://pdbe.org/1i3j PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1i3j RCSB], [https://www.ebi.ac.uk/pdbsum/1i3j PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1i3j ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/TEV1_BPT4 TEV1_BPT4] This endonuclease is specific to the thymidylate synthase (td) gene splice junction and is involved in intron homing.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/i3/1i3j_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1i3j ConSurf].
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<div style="clear:both"></div>
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===CRYSTAL STRUCTURE OF THE DNA-BINDING DOMAIN OF INTRON ENDONUCLEASE I-TEVI WITH ITS SUBSTRATE===
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==See Also==
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*[[Endonuclease 3D structures|Endonuclease 3D structures]]
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__TOC__
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_11447104}}, adds the Publication Abstract to the page
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[[Category: Escherichia virus T4]]
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(as it appears on PubMed at http://www.pubmed.gov), where 11447104 is the PubMed ID number.
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[[Category: Large Structures]]
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[[Category: Belfort M]]
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{{ABSTRACT_PUBMED_11447104}}
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[[Category: Derbyshire V]]
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[[Category: Fox KM]]
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==About this Structure==
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[[Category: Van Roey P]]
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1I3J is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Enterobacteria_phage_t4 Enterobacteria phage t4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1I3J OCA].
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[[Category: Waddling CA]]
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==Reference==
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Intertwined structure of the DNA-binding domain of intron endonuclease I-TevI with its substrate., Van Roey P, Waddling CA, Fox KM, Belfort M, Derbyshire V, EMBO J. 2001 Jul 16;20(14):3631-7. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11447104 11447104]
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[[Category: Enterobacteria phage t4]]
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[[Category: Single protein]]
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[[Category: Belfort, M.]]
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[[Category: Derbyshire, V.]]
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[[Category: Fox, K M.]]
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[[Category: Roey, P Van.]]
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[[Category: Waddling, C A.]]
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[[Category: Extended structure]]
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[[Category: Helix-turn-helix]]
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[[Category: Minor groove helix]]
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[[Category: Protein-dna complex]]
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[[Category: Zn-finger]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 10:21:33 2008''
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Current revision

CRYSTAL STRUCTURE OF THE DNA-BINDING DOMAIN OF INTRON ENDONUCLEASE I-TEVI WITH ITS SUBSTRATE

PDB ID 1i3j

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