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1i5e

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{{Seed}}
 
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[[Image:1i5e.png|left|200px]]
 
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==CRYSTAL STRUCTURE OF BACILLUS CALDOLYTICUS URACIL PHOSPHORIBOSYLTRANSFERASE WITH BOUND UMP==
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The line below this paragraph, containing "STRUCTURE_1i5e", creates the "Structure Box" on the page.
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<StructureSection load='1i5e' size='340' side='right'caption='[[1i5e]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1i5e]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_caldolyticus Bacillus caldolyticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1I5E OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1I5E FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=U5P:URIDINE-5-MONOPHOSPHATE'>U5P</scene></td></tr>
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{{STRUCTURE_1i5e| PDB=1i5e | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1i5e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1i5e OCA], [https://pdbe.org/1i5e PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1i5e RCSB], [https://www.ebi.ac.uk/pdbsum/1i5e PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1i5e ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/UPP_BACCL UPP_BACCL] Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.<ref>PMID:12037295</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/i5/1i5e_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1i5e ConSurf].
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<div style="clear:both"></div>
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===CRYSTAL STRUCTURE OF BACILLUS CALDOLYTICUS URACIL PHOSPHORIBOSYLTRANSFERASE WITH BOUND UMP===
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==See Also==
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*[[Phosphoribosyltransferase 3D structures|Phosphoribosyltransferase 3D structures]]
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== References ==
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<references/>
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The line below this paragraph, {{ABSTRACT_PUBMED_12037295}}, adds the Publication Abstract to the page
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__TOC__
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(as it appears on PubMed at http://www.pubmed.gov), where 12037295 is the PubMed ID number.
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</StructureSection>
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[[Category: Large Structures]]
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{{ABSTRACT_PUBMED_12037295}}
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[[Category: Kadziola A]]
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[[Category: Larsen S]]
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==About this Structure==
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[[Category: Neuhard J]]
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1I5E is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Bacillus_caldolyticus Bacillus caldolyticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1I5E OCA].
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==Reference==
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Structure of product-bound Bacillus caldolyticus uracil phosphoribosyltransferase confirms ordered sequential substrate binding., Kadziola A, Neuhard J, Larsen S, Acta Crystallogr D Biol Crystallogr. 2002 Jun;58(Pt 6 Pt 2):936-45. Epub, 2002 May 29. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12037295 12037295]
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[[Category: Bacillus caldolyticus]]
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[[Category: Single protein]]
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[[Category: Uracil phosphoribosyltransferase]]
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[[Category: Kadziola, A.]]
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[[Category: Larsen, S.]]
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[[Category: Neuhard, J.]]
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[[Category: Bacillus caldolyticus]]
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[[Category: Salvage pathway]]
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[[Category: Uracil phosphoribosyltransferase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 10:26:47 2008''
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Current revision

CRYSTAL STRUCTURE OF BACILLUS CALDOLYTICUS URACIL PHOSPHORIBOSYLTRANSFERASE WITH BOUND UMP

PDB ID 1i5e

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