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1i6w

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[[Image:1i6w.png|left|200px]]
 
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{{STRUCTURE_1i6w| PDB=1i6w | SCENE= }}
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==THE CRYSTAL STRUCTURE OF BACILLUS SUBTILIS LIPASE: A MINIMAL ALPHA/BETA HYDROLASE ENZYME==
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<StructureSection load='1i6w' size='340' side='right'caption='[[1i6w]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
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===THE CRYSTAL STRUCTURE OF BACILLUS SUBTILIS LIPASE: A MINIMAL ALPHA/BETA HYDROLASE ENZYME===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1i6w]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1I6W OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1I6W FirstGlance]. <br>
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{{ABSTRACT_PUBMED_11491291}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CD:CADMIUM+ION'>CD</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1i6w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1i6w OCA], [https://pdbe.org/1i6w PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1i6w RCSB], [https://www.ebi.ac.uk/pdbsum/1i6w PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1i6w ProSAT]</span></td></tr>
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[[1i6w]] is a 2 chain structure of [[Lipase]] with sequence from [http://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1I6W OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/ESTA_BACSU ESTA_BACSU] Active toward p-nitrophenyl esters and triacylglycerides with a marked preference for esters with C8 acyl groups.<ref>PMID:8396026</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/i6/1i6w_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1i6w ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Lipase|Lipase]]
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*[[Lipase 3D Structures|Lipase 3D Structures]]
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== References ==
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==Reference==
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<references/>
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<ref group="xtra">PMID:011491291</ref><references group="xtra"/>
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__TOC__
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</StructureSection>
[[Category: Bacillus subtilis]]
[[Category: Bacillus subtilis]]
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[[Category: Triacylglycerol lipase]]
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[[Category: Large Structures]]
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[[Category: Dijkstra, B W.]]
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[[Category: Dijkstra BW]]
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[[Category: Eggert, T.]]
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[[Category: Eggert T]]
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[[Category: Jaeger, K E.]]
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[[Category: Jaeger K-E]]
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[[Category: Pouderoyen, G van.]]
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[[Category: Van Pouderoyen G]]
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[[Category: Alpha/beta hydrolase]]
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[[Category: Hydrolase]]
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Current revision

THE CRYSTAL STRUCTURE OF BACILLUS SUBTILIS LIPASE: A MINIMAL ALPHA/BETA HYDROLASE ENZYME

PDB ID 1i6w

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