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1i8d

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{{Seed}}
 
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[[Image:1i8d.png|left|200px]]
 
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==CRYSTAL STRUCTURE OF RIBOFLAVIN SYNTHASE==
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The line below this paragraph, containing "STRUCTURE_1i8d", creates the "Structure Box" on the page.
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<StructureSection load='1i8d' size='340' side='right'caption='[[1i8d]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1i8d]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1I8D OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1I8D FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1i8d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1i8d OCA], [https://pdbe.org/1i8d PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1i8d RCSB], [https://www.ebi.ac.uk/pdbsum/1i8d PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1i8d ProSAT]</span></td></tr>
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{{STRUCTURE_1i8d| PDB=1i8d | SCENE= }}
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</table>
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== Function ==
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===CRYSTAL STRUCTURE OF RIBOFLAVIN SYNTHASE===
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[https://www.uniprot.org/uniprot/RISA_ECOLI RISA_ECOLI] Catalyzes the dismutation of two molecules of 6,7-dimethyl-8-ribityllumazine, resulting in the formation of riboflavin and 5-amino-6-(D-ribitylamino)uracil.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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<!--
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Check<jmol>
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The line below this paragraph, {{ABSTRACT_PUBMED_11377200}}, adds the Publication Abstract to the page
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<jmolCheckbox>
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(as it appears on PubMed at http://www.pubmed.gov), where 11377200 is the PubMed ID number.
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/i8/1i8d_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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{{ABSTRACT_PUBMED_11377200}}
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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==About this Structure==
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1i8d ConSurf].
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1I8D is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1I8D OCA].
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<div style="clear:both"></div>
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__TOC__
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==Reference==
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</StructureSection>
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Crystal structure of riboflavin synthase., Liao DI, Wawrzak Z, Calabrese JC, Viitanen PV, Jordan DB, Structure. 2001 May 9;9(5):399-408. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11377200 11377200]
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[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Riboflavin synthase]]
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[[Category: Large Structures]]
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[[Category: Single protein]]
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[[Category: Calabrese JC]]
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[[Category: Calabrese, J C.]]
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[[Category: Jordan DB]]
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[[Category: Jordan, D B.]]
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[[Category: Liao D-I]]
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[[Category: Liao, D I.]]
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[[Category: Viitanen PV]]
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[[Category: Viitanen, P V.]]
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[[Category: Wawrzak Z]]
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[[Category: Wawrzak, Z.]]
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[[Category: Antimicrobial target]]
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[[Category: Escherichia coli]]
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[[Category: Riboflavin biosynthesis]]
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[[Category: Riboflavin synthase]]
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[[Category: Structure-based design]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 10:34:39 2008''
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Current revision

CRYSTAL STRUCTURE OF RIBOFLAVIN SYNTHASE

PDB ID 1i8d

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