This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.


Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1iho

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
m (Protected "1iho" [edit=sysop:move=sysop])
Current revision (07:35, 7 February 2024) (edit) (undo)
 
(9 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:1iho.png|left|200px]]
 
-
{{STRUCTURE_1iho| PDB=1iho | SCENE= }}
+
==CRYSTAL APO-STRUCTURE OF PANTOTHENATE SYNTHETASE FROM E. COLI==
 +
<StructureSection load='1iho' size='340' side='right'caption='[[1iho]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
 +
== Structural highlights ==
 +
<table><tr><td colspan='2'>[[1iho]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IHO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1IHO FirstGlance]. <br>
 +
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
 +
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr>
 +
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1iho FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1iho OCA], [https://pdbe.org/1iho PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1iho RCSB], [https://www.ebi.ac.uk/pdbsum/1iho PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1iho ProSAT]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/PANC_ECOLI PANC_ECOLI] Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.<ref>PMID:357689</ref>
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ih/1iho_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1iho ConSurf].
 +
<div style="clear:both"></div>
-
===CRYSTAL APO-STRUCTURE OF PANTOTHENATE SYNTHETASE FROM E. COLI===
+
==See Also==
-
 
+
*[[Pantothenate synthetase|Pantothenate synthetase]]
-
{{ABSTRACT_PUBMED_11377204}}
+
== References ==
-
 
+
<references/>
-
==About this Structure==
+
__TOC__
-
[[1iho]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IHO OCA].
+
</StructureSection>
-
 
+
-
==Reference==
+
-
<ref group="xtra">PMID:011377204</ref><ref group="xtra">PMID:017554169</ref><references group="xtra"/>
+
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
-
[[Category: Pantoate--beta-alanine ligase]]
+
[[Category: Large Structures]]
-
[[Category: Abell, C.]]
+
[[Category: Abell C]]
-
[[Category: Blundell, T L.]]
+
[[Category: Blundell TL]]
-
[[Category: Delft, F von.]]
+
[[Category: Dhanaraj V]]
-
[[Category: Dhanaraj, V.]]
+
[[Category: Lewendon A]]
-
[[Category: Lewendon, A.]]
+
[[Category: Smith A]]
-
[[Category: Smith, A.]]
+
[[Category: Von Delft F]]
-
[[Category: Apo]]
+
-
[[Category: Dimer]]
+
-
[[Category: Flexible domain]]
+
-
[[Category: High]]
+
-
[[Category: Ksmk]]
+
-
[[Category: Ligase]]
+
-
[[Category: Multidomain]]
+
-
[[Category: Rossman fold]]
+

Current revision

CRYSTAL APO-STRUCTURE OF PANTOTHENATE SYNTHETASE FROM E. COLI

PDB ID 1iho

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools