This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1iir

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (07:36, 7 February 2024) (edit) (undo)
 
(11 intermediate revisions not shown.)
Line 1: Line 1:
-
{{Seed}}
 
-
[[Image:1iir.png|left|200px]]
 
-
<!--
+
==Crystal Structure of UDP-glucosyltransferase GtfB==
-
The line below this paragraph, containing "STRUCTURE_1iir", creates the "Structure Box" on the page.
+
<StructureSection load='1iir' size='340' side='right'caption='[[1iir]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[1iir]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Amycolatopsis_orientalis Amycolatopsis orientalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IIR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1IIR FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
-
-->
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-
{{STRUCTURE_1iir| PDB=1iir | SCENE= }}
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1iir FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1iir OCA], [https://pdbe.org/1iir PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1iir RCSB], [https://www.ebi.ac.uk/pdbsum/1iir PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1iir ProSAT]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/GTFB_AMYOR GTFB_AMYOR] Glucosyltransferase that transfers glucose to the 4-OH-Phegly(4) residue of vancomycin aglycone (AGV) to produce devancoaminyl-vancomycin (DVV) in the biosynthesis of glycopeptide antibiotic chloroeremomycin, a member of the vancomycin group of antibiotics.<ref>PMID:11294642</ref> <ref>PMID:9115410</ref>
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ii/1iir_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1iir ConSurf].
 +
<div style="clear:both"></div>
-
===Crystal Structure of UDP-glucosyltransferase GtfB===
+
==See Also==
-
 
+
*[[Glycosyltransferase 3D structures|Glycosyltransferase 3D structures]]
-
 
+
== References ==
-
<!--
+
<references/>
-
The line below this paragraph, {{ABSTRACT_PUBMED_11470430}}, adds the Publication Abstract to the page
+
__TOC__
-
(as it appears on PubMed at http://www.pubmed.gov), where 11470430 is the PubMed ID number.
+
</StructureSection>
-
-->
+
-
{{ABSTRACT_PUBMED_11470430}}
+
-
 
+
-
==About this Structure==
+
-
1IIR is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Amycolatopsis_orientalis Amycolatopsis orientalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IIR OCA].
+
-
 
+
-
==Reference==
+
-
Structure of the UDP-glucosyltransferase GtfB that modifies the heptapeptide aglycone in the biosynthesis of vancomycin group antibiotics., Mulichak AM, Losey HC, Walsh CT, Garavito RM, Structure. 2001 Jul 3;9(7):547-57. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11470430 11470430]
+
[[Category: Amycolatopsis orientalis]]
[[Category: Amycolatopsis orientalis]]
-
[[Category: Single protein]]
+
[[Category: Large Structures]]
-
[[Category: Garavito, R M.]]
+
[[Category: Garavito RM]]
-
[[Category: Losey, H C.]]
+
[[Category: Losey HC]]
-
[[Category: Mulichak, A M.]]
+
[[Category: Mulichak AM]]
-
[[Category: Walsh, C T.]]
+
[[Category: Walsh CT]]
-
[[Category: Glycosyltransferase]]
+
-
[[Category: Rossmann fold]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 12:17:41 2008''
+

Current revision

Crystal Structure of UDP-glucosyltransferase GtfB

PDB ID 1iir

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1iir"
Personal tools