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1jax

From Proteopedia

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{{Seed}}
 
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[[Image:1jax.png|left|200px]]
 
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<!--
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==Structure of Coenzyme F420H2:NADP+ Oxidoreductase (FNO)==
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The line below this paragraph, containing "STRUCTURE_1jax", creates the "Structure Box" on the page.
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<StructureSection load='1jax' size='340' side='right'caption='[[1jax]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1jax]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Archaeoglobus_fulgidus Archaeoglobus fulgidus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JAX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1JAX FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
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{{STRUCTURE_1jax| PDB=1jax | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1jax FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jax OCA], [https://pdbe.org/1jax PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1jax RCSB], [https://www.ebi.ac.uk/pdbsum/1jax PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1jax ProSAT]</span></td></tr>
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</table>
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===Structure of Coenzyme F420H2:NADP+ Oxidoreductase (FNO)===
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== Function ==
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[https://www.uniprot.org/uniprot/FNO_ARCFU FNO_ARCFU] Catalyzes the reversible reduction of NADP(+) by F420H(2). In this reaction the proS hydrogen at C5 of F420 is transferred into the proS position at C4 of NADPH.<ref>PMID:11726492</ref> [REFERENCE:2]
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== Evolutionary Conservation ==
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<!--
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[[Image:Consurf_key_small.gif|200px|right]]
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The line below this paragraph, {{ABSTRACT_PUBMED_11726492}}, adds the Publication Abstract to the page
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Check<jmol>
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(as it appears on PubMed at http://www.pubmed.gov), where 11726492 is the PubMed ID number.
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ja/1jax_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_11726492}}
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==About this Structure==
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</jmolCheckbox>
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1JAX is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Archaeoglobus_fulgidus Archaeoglobus fulgidus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JAX OCA].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1jax ConSurf].
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<div style="clear:both"></div>
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==Reference==
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== References ==
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Structures of F420H2:NADP+ oxidoreductase with and without its substrates bound., Warkentin E, Mamat B, Sordel-Klippert M, Wicke M, Thauer RK, Iwata M, Iwata S, Ermler U, Shima S, EMBO J. 2001 Dec 3;20(23):6561-9. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11726492 11726492]
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<references/>
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__TOC__
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</StructureSection>
[[Category: Archaeoglobus fulgidus]]
[[Category: Archaeoglobus fulgidus]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Ermler, U.]]
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[[Category: Ermler U]]
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[[Category: Mamat, B.]]
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[[Category: Mamat B]]
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[[Category: Shima, S.]]
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[[Category: Shima S]]
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[[Category: Thauer, R.]]
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[[Category: Thauer R]]
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[[Category: Warkentin, E.]]
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[[Category: Warkentin E]]
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[[Category: Rossman fold]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 00:42:19 2008''
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Current revision

Structure of Coenzyme F420H2:NADP+ Oxidoreductase (FNO)

PDB ID 1jax

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