1jjo

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{{Seed}}
 
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[[Image:1jjo.png|left|200px]]
 
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==Crystal Structure of Mouse Neuroserpin (Cleaved form)==
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The line below this paragraph, containing "STRUCTURE_1jjo", creates the "Structure Box" on the page.
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<StructureSection load='1jjo' size='340' side='right'caption='[[1jjo]], [[Resolution|resolution]] 3.06&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1jjo]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JJO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1JJO FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.06&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1jjo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jjo OCA], [https://pdbe.org/1jjo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1jjo RCSB], [https://www.ebi.ac.uk/pdbsum/1jjo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1jjo ProSAT]</span></td></tr>
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{{STRUCTURE_1jjo| PDB=1jjo | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/NEUS_MOUSE NEUS_MOUSE] Serine protease inhibitor that inhibits plasminogen activators and plasmin but not thrombin. May be involved in the formation or reorganization of synaptic connections as well as for synaptic plasticity in the adult nervous system. May protect neurons from cell damage by tissue-type plasminogen activator.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jj/1jjo_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1jjo ConSurf].
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<div style="clear:both"></div>
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===Crystal Structure of Mouse Neuroserpin (Cleaved form)===
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==See Also==
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*[[Serpin 3D structures|Serpin 3D structures]]
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__TOC__
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_11557034}}, adds the Publication Abstract to the page
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[[Category: Large Structures]]
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(as it appears on PubMed at http://www.pubmed.gov), where 11557034 is the PubMed ID number.
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{{ABSTRACT_PUBMED_11557034}}
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==About this Structure==
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1JJO is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JJO OCA].
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==Reference==
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Crystal structure of neuroserpin: a neuronal serpin involved in a conformational disease., Briand C, Kozlov SV, Sonderegger P, Grutter MG, FEBS Lett. 2001 Sep 7;505(1):18-22. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11557034 11557034]
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[[Category: Mus musculus]]
[[Category: Mus musculus]]
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[[Category: Protein complex]]
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[[Category: Briand C]]
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[[Category: Briand, C.]]
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[[Category: Gruetter MG]]
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[[Category: Gruetter, M G.]]
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[[Category: Kozlov SV]]
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[[Category: Kozlov, S V.]]
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[[Category: Sonderegger P]]
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[[Category: Sonderegger, P.]]
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[[Category: Neuronal serpin]]
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[[Category: Serine protease inhibitor]]
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[[Category: Serpin]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 20:20:56 2008''
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Current revision

Crystal Structure of Mouse Neuroserpin (Cleaved form)

PDB ID 1jjo

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