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1jop
From Proteopedia
(Difference between revisions)
(New page: 200px<br /><applet load="1jop" size="450" color="white" frame="true" align="right" spinBox="true" caption="1jop, resolution 2.60Å" /> '''YHCH protein (HI0227...) |
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| - | [[Image:1jop.jpg|left|200px]]<br /><applet load="1jop" size="450" color="white" frame="true" align="right" spinBox="true" | ||
| - | caption="1jop, resolution 2.60Å" /> | ||
| - | '''YHCH protein (HI0227)'''<br /> | ||
| - | == | + | ==YHCH protein (HI0227)== |
| - | + | <StructureSection load='1jop' size='340' side='right'caption='[[1jop]], [[Resolution|resolution]] 2.60Å' scene=''> | |
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[1jop]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Haemophilus_influenzae Haemophilus influenzae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JOP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1JOP FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HG:MERCURY+(II)+ION'>HG</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1jop FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jop OCA], [https://pdbe.org/1jop PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1jop RCSB], [https://www.ebi.ac.uk/pdbsum/1jop PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1jop ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/NANQ_HAEIN NANQ_HAEIN] Opens both the alpha- and beta-forms of N-acetylneuraminate (sialic acid; Neu5Ac) to provide aceneuramate, the preferred substrate for NanA (Probable). Has preferential activity on the beta-anomer rather than the alpha-anomer. Accelerates a reaction that is spontaneous at slightly alkaline pH, facilitates the reaction at acidic pH (By similarity).[UniProtKB:P45424]<ref>PMID:33895133</ref> | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jo/1jop_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1jop ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Haemophilus influenzae]] | [[Category: Haemophilus influenzae]] | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: Gilliland | + | [[Category: Gilliland GL]] |
| - | [[Category: Obmolova | + | [[Category: Obmolova G]] |
| - | + | [[Category: Teplyakov A]] | |
| - | [[Category: Teplyakov | + | |
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Current revision
YHCH protein (HI0227)
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