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1jyf

From Proteopedia

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{{Seed}}
 
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[[Image:1jyf.png|left|200px]]
 
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==Structure of the Dimeric Lac Repressor with an 11-residue C-terminal Deletion.==
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The line below this paragraph, containing "STRUCTURE_1jyf", creates the "Structure Box" on the page.
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<StructureSection load='1jyf' size='340' side='right'caption='[[1jyf]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1jyf]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JYF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1JYF FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
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{{STRUCTURE_1jyf| PDB=1jyf | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1jyf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jyf OCA], [https://pdbe.org/1jyf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1jyf RCSB], [https://www.ebi.ac.uk/pdbsum/1jyf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1jyf ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/LACI_ECOLI LACI_ECOLI] Repressor of the lactose operon. Binds allolactose as an inducer.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jy/1jyf_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1jyf ConSurf].
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<div style="clear:both"></div>
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===Structure of the Dimeric Lac Repressor with an 11-residue C-terminal Deletion.===
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==See Also==
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*[[Lac repressor|Lac repressor]]
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__TOC__
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<!--
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_11601849}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 11601849 is the PubMed ID number.
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{{ABSTRACT_PUBMED_11601849}}
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==About this Structure==
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1JYF is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JYF OCA].
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==Reference==
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Structure of a variant of lac repressor with increased thermostability and decreased affinity for operator., Bell CE, Barry J, Matthews KS, Lewis M, J Mol Biol. 2001 Oct 12;313(1):99-109. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11601849 11601849]
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[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Barry, J.]]
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[[Category: Barry J]]
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[[Category: Bell, C E.]]
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[[Category: Bell CE]]
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[[Category: Lewis, M.]]
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[[Category: Lewis M]]
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[[Category: Matthews, K S.]]
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[[Category: Matthews KS]]
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[[Category: Gene regulation]]
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[[Category: Protein dna-binding]]
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[[Category: Protein stability]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 21:06:14 2008''
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Current revision

Structure of the Dimeric Lac Repressor with an 11-residue C-terminal Deletion.

PDB ID 1jyf

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