1k0e

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{{Seed}}
 
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[[Image:1k0e.png|left|200px]]
 
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==THE CRYSTAL STRUCTURE OF AMINODEOXYCHORISMATE SYNTHASE FROM FORMATE GROWN CRYSTALS==
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The line below this paragraph, containing "STRUCTURE_1k0e", creates the "Structure Box" on the page.
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<StructureSection load='1k0e' size='340' side='right'caption='[[1k0e]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1k0e]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1K0E OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1K0E FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=TRP:TRYPTOPHAN'>TRP</scene></td></tr>
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{{STRUCTURE_1k0e| PDB=1k0e | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1k0e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1k0e OCA], [https://pdbe.org/1k0e PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1k0e RCSB], [https://www.ebi.ac.uk/pdbsum/1k0e PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1k0e ProSAT]</span></td></tr>
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</table>
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===THE CRYSTAL STRUCTURE OF AMINODEOXYCHORISMATE SYNTHASE FROM FORMATE GROWN CRYSTALS===
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== Function ==
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[https://www.uniprot.org/uniprot/PABB_ECOLI PABB_ECOLI] Part of a heterodimeric complex that catalyzes the two-step biosynthesis of 4-amino-4-deoxychorismate (ADC), a precursor of p-aminobenzoate (PABA) and tetrahydrofolate. In the first step, a glutamine amidotransferase (PabA) generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by aminodeoxychorismate synthase (PabB) to produce ADC. PabB, in the absence of PabA, can catalyze the formation of ADC in the presence of exogenous ammonia.<ref>PMID:4914080</ref> <ref>PMID:2251281</ref> <ref>PMID:16605270</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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(as it appears on PubMed at http://www.pubmed.gov), where 11841211 is the PubMed ID number.
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/k0/1k0e_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_11841211}}
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==About this Structure==
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</jmolCheckbox>
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1K0E is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1K0E OCA].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1k0e ConSurf].
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<div style="clear:both"></div>
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==Reference==
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== References ==
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<ref group="xtra">PMID:11841211</ref><references group="xtra"/>
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<references/>
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__TOC__
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</StructureSection>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Eisenstein, E.]]
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[[Category: Large Structures]]
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[[Category: Howard, A J.]]
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[[Category: Eisenstein E]]
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[[Category: Jensen, P Y.]]
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[[Category: Howard AJ]]
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[[Category: Ladner, J E.]]
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[[Category: Jensen PY]]
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[[Category: Pachikara, A S.]]
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[[Category: Ladner JE]]
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[[Category: Parsons, J F.]]
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[[Category: Pachikara AS]]
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[[Category: Aminodeoxychorismate synthase]]
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[[Category: Parsons JF]]
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[[Category: Chorismate]]
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[[Category: Glutamine]]
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[[Category: P-aminobenzoate synthase]]
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[[Category: Paba synthase]]
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[[Category: Tryptophan]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 05:44:18 2009''
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Current revision

THE CRYSTAL STRUCTURE OF AMINODEOXYCHORISMATE SYNTHASE FROM FORMATE GROWN CRYSTALS

PDB ID 1k0e

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