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1k46

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[[Image:1k46.png|left|200px]]
 
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{{STRUCTURE_1k46| PDB=1k46 | SCENE= }}
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==Crystal Structure of the Type III Secretory Domain of Yersinia YopH Reveals a Domain-Swapped Dimer==
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<StructureSection load='1k46' size='340' side='right'caption='[[1k46]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
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===Crystal Structure of the Type III Secretory Domain of Yersinia YopH Reveals a Domain-Swapped Dimer===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1k46]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Yersinia_pseudotuberculosis Yersinia pseudotuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1K46 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1K46 FirstGlance]. <br>
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{{ABSTRACT_PUBMED_11737640}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1k46 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1k46 OCA], [https://pdbe.org/1k46 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1k46 RCSB], [https://www.ebi.ac.uk/pdbsum/1k46 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1k46 ProSAT]</span></td></tr>
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==About this Structure==
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</table>
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[[1k46]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Yersinia_pseudotuberculosis Yersinia pseudotuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1K46 OCA].
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== Function ==
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[https://www.uniprot.org/uniprot/YOPH_YERPS YOPH_YERPS] Essential virulence determinant. This protein is a protein tyrosine phosphatase. The essential function of YopH in Yersinia pathogenesis is host-protein dephosphorylation. It contributes to the ability of the bacteria to resist phagocytosis by peritoneal macrophages.
==See Also==
==See Also==
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*[[Tyrosine phosphatase|Tyrosine phosphatase]]
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*[[Tyrosine phosphatase 3D structures|Tyrosine phosphatase 3D structures]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:011737640</ref><references group="xtra"/>
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[[Category: Large Structures]]
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[[Category: Protein-tyrosine-phosphatase]]
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[[Category: Yersinia pseudotuberculosis]]
[[Category: Yersinia pseudotuberculosis]]
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[[Category: Keliikuli, K.]]
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[[Category: Keliikuli K]]
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[[Category: Khandelwal, P.]]
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[[Category: Khandelwal P]]
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[[Category: Saper, M A.]]
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[[Category: Saper MA]]
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[[Category: Smith, C L.]]
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[[Category: Smith CL]]
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[[Category: Zuiderweg, E R.P.]]
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[[Category: Zuiderweg ERP]]
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[[Category: Domain-swap]]
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[[Category: Hydrolase]]
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[[Category: Phosphopeptide-binding domain]]
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[[Category: Type iii secretion domain]]
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Current revision

Crystal Structure of the Type III Secretory Domain of Yersinia YopH Reveals a Domain-Swapped Dimer

PDB ID 1k46

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