1k5j
From Proteopedia
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| - | [[Image:1k5j.png|left|200px]] | ||
| - | + | ==The Crystal Structure of Nucleoplasmin-Core== | |
| - | + | <StructureSection load='1k5j' size='340' side='right'caption='[[1k5j]], [[Resolution|resolution]] 2.30Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[1k5j]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Xenopus_laevis Xenopus laevis]. The January 2007 RCSB PDB [https://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Importins'' by David S. Goodsell is [https://dx.doi.org/10.2210/rcsb_pdb/mom_2007_1 10.2210/rcsb_pdb/mom_2007_1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1K5J OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1K5J FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3Å</td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1k5j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1k5j OCA], [https://pdbe.org/1k5j PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1k5j RCSB], [https://www.ebi.ac.uk/pdbsum/1k5j PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1k5j ProSAT]</span></td></tr> | |
| - | == | + | </table> |
| - | [[1k5j]] is a 5 chain structure | + | == Function == |
| + | [https://www.uniprot.org/uniprot/NUPL_XENLA NUPL_XENLA] Core histones chaperone involved in chromatin reprogramming, specially during fertilization and early embryonic development. Nucleoplasmin is an acidic protein which is able to assemble nucleosomes by binding histones and transferring them to DNA. | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/k5/1k5j_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1k5j ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
==See Also== | ==See Also== | ||
*[[Nucleoplasmin|Nucleoplasmin]] | *[[Nucleoplasmin|Nucleoplasmin]] | ||
| - | + | __TOC__ | |
| - | + | </StructureSection> | |
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[[Category: Importins]] | [[Category: Importins]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: RCSB PDB Molecule of the Month]] | [[Category: RCSB PDB Molecule of the Month]] | ||
[[Category: Xenopus laevis]] | [[Category: Xenopus laevis]] | ||
| - | [[Category: Akey | + | [[Category: Akey CW]] |
| - | [[Category: Akey | + | [[Category: Akey IV]] |
| - | [[Category: Dingwall | + | [[Category: Dingwall C]] |
| - | [[Category: Dutta | + | [[Category: Dutta S]] |
| - | [[Category: Hartman | + | [[Category: Hartman KL]] |
| - | [[Category: Head | + | [[Category: Head JF]] |
| - | [[Category: Laue | + | [[Category: Laue T]] |
| - | [[Category: Nolte | + | [[Category: Nolte RT]] |
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Current revision
The Crystal Structure of Nucleoplasmin-Core
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