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1k70

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{{Seed}}
 
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[[Image:1k70.png|left|200px]]
 
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==The Structure of Escherichia coli Cytosine Deaminase bound to 4-Hydroxy-3,4-Dihydro-1H-Pyrimidin-2-one==
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The line below this paragraph, containing "STRUCTURE_1k70", creates the "Structure Box" on the page.
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<StructureSection load='1k70' size='340' side='right'caption='[[1k70]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1k70]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1K70 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1K70 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=HPY:4-HYDROXY-3,4-DIHYDRO-1H-PYRIMIDIN-2-ONE'>HPY</scene></td></tr>
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{{STRUCTURE_1k70| PDB=1k70 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1k70 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1k70 OCA], [https://pdbe.org/1k70 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1k70 RCSB], [https://www.ebi.ac.uk/pdbsum/1k70 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1k70 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/CODA_ECOLI CODA_ECOLI]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/k7/1k70_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1k70 ConSurf].
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<div style="clear:both"></div>
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===The Structure of Escherichia coli Cytosine Deaminase bound to 4-Hydroxy-3,4-Dihydro-1H-Pyrimidin-2-one===
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==See Also==
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*[[Deaminase 3D structures|Deaminase 3D structures]]
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__TOC__
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_11812140}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 11812140 is the PubMed ID number.
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{{ABSTRACT_PUBMED_11812140}}
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==About this Structure==
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1K70 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1K70 OCA].
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==Reference==
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The structure of Escherichia coli cytosine deaminase., Ireton GC, McDermott G, Black ME, Stoddard BL, J Mol Biol. 2002 Jan 25;315(4):687-97. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11812140 11812140]
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[[Category: Cytosine deaminase]]
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[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Black, M E.]]
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[[Category: Black ME]]
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[[Category: Ireton, G C.]]
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[[Category: Ireton GC]]
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[[Category: McDermott, G.]]
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[[Category: McDermott G]]
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[[Category: Stoddard, B L.]]
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[[Category: Stoddard BL]]
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[[Category: Alpha-beta barrel]]
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[[Category: Conformational change]]
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[[Category: Cytosine deaminase]]
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[[Category: Hexamer]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 2 09:52:48 2008''
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Current revision

The Structure of Escherichia coli Cytosine Deaminase bound to 4-Hydroxy-3,4-Dihydro-1H-Pyrimidin-2-one

PDB ID 1k70

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