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1kcx
From Proteopedia
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| - | [[Image:1kcx.png|left|200px]] | ||
| - | + | ==X-ray structure of NYSGRC target T-45== | |
| - | + | <StructureSection load='1kcx' size='340' side='right'caption='[[1kcx]], [[Resolution|resolution]] 2.12Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[1kcx]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KCX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1KCX FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.12Å</td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1kcx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1kcx OCA], [https://pdbe.org/1kcx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1kcx RCSB], [https://www.ebi.ac.uk/pdbsum/1kcx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1kcx ProSAT], [https://www.topsan.org/Proteins/NYSGXRC/1kcx TOPSAN]</span></td></tr> | |
| - | == | + | </table> |
| - | [[1kcx]] is a 2 chain structure with sequence from [ | + | == Function == |
| - | + | [https://www.uniprot.org/uniprot/DPYL1_MOUSE DPYL1_MOUSE] Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration.<ref>PMID:14685275</ref> | |
| - | == | + | == Evolutionary Conservation == |
| - | < | + | [[Image:Consurf_key_small.gif|200px|right]] |
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/kc/1kcx_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1kcx ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
[[Category: Mus musculus]] | [[Category: Mus musculus]] | ||
| - | [[Category: Burley | + | [[Category: Burley SK]] |
| - | [[Category: Deo | + | [[Category: Deo RC]] |
| - | + | [[Category: Schmidt EF]] | |
| - | [[Category: Schmidt | + | [[Category: Strittmatter SM]] |
| - | [[Category: Strittmatter | + | |
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Current revision
X-ray structure of NYSGRC target T-45
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