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1kcx

From Proteopedia

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{{Seed}}
 
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[[Image:1kcx.png|left|200px]]
 
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<!--
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==X-ray structure of NYSGRC target T-45==
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The line below this paragraph, containing "STRUCTURE_1kcx", creates the "Structure Box" on the page.
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<StructureSection load='1kcx' size='340' side='right'caption='[[1kcx]], [[Resolution|resolution]] 2.12&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1kcx]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KCX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1KCX FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.12&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1kcx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1kcx OCA], [https://pdbe.org/1kcx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1kcx RCSB], [https://www.ebi.ac.uk/pdbsum/1kcx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1kcx ProSAT], [https://www.topsan.org/Proteins/NYSGXRC/1kcx TOPSAN]</span></td></tr>
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{{STRUCTURE_1kcx| PDB=1kcx | SCENE= }}
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</table>
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== Function ==
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===X-ray structure of NYSGRC target T-45===
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[https://www.uniprot.org/uniprot/DPYL1_MOUSE DPYL1_MOUSE] Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration.<ref>PMID:14685275</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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<!--
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Check<jmol>
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The line below this paragraph, {{ABSTRACT_PUBMED_14685275}}, adds the Publication Abstract to the page
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<jmolCheckbox>
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(as it appears on PubMed at http://www.pubmed.gov), where 14685275 is the PubMed ID number.
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/kc/1kcx_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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{{ABSTRACT_PUBMED_14685275}}
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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==About this Structure==
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1kcx ConSurf].
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1KCX is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KCX OCA].
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<div style="clear:both"></div>
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== References ==
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==Reference==
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<references/>
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Structural bases for CRMP function in plexin-dependent semaphorin3A signaling., Deo RC, Schmidt EF, Elhabazi A, Togashi H, Burley SK, Strittmatter SM, EMBO J. 2004 Jan 14;23(1):9-22. Epub 2003 Dec 18. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/14685275 14685275]
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
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[[Category: Single protein]]
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[[Category: Burley SK]]
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[[Category: Burley, S K.]]
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[[Category: Deo RC]]
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[[Category: Deo, R C.]]
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[[Category: Schmidt EF]]
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[[Category: NYSGXRC, New York Structural GenomiX Research Consortium.]]
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[[Category: Strittmatter SM]]
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[[Category: Schmidt, E F.]]
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[[Category: Strittmatter, S M.]]
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[[Category: Alpha/beta barrel]]
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[[Category: New york structural genomix research consortium]]
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[[Category: Nysgxrc]]
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[[Category: Protein structure initiative]]
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[[Category: Psi]]
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[[Category: Structural genomic]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 2 10:08:52 2008''
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Current revision

X-ray structure of NYSGRC target T-45

PDB ID 1kcx

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