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2vkr

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{{Seed}}
 
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[[Image:2vkr.png|left|200px]]
 
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==3Fe-4S, 4Fe-4S plus Zn Acidianus ambivalens ferredoxin==
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The line below this paragraph, containing "STRUCTURE_2vkr", creates the "Structure Box" on the page.
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<StructureSection load='2vkr' size='340' side='right'caption='[[2vkr]], [[Resolution|resolution]] 2.01&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2vkr]] is a 7 chain structure with sequence from [https://en.wikipedia.org/wiki/Acidianus_ambivalens Acidianus ambivalens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VKR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2VKR FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.01&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=F3S:FE3-S4+CLUSTER'>F3S</scene>, <scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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{{STRUCTURE_2vkr| PDB=2vkr | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2vkr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vkr OCA], [https://pdbe.org/2vkr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2vkr RCSB], [https://www.ebi.ac.uk/pdbsum/2vkr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2vkr ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/FER_ACIAM FER_ACIAM] Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. The 3Fe-4S cluster is reduced by a flavoprotein with NADH oxidase activity from the same organism.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/vk/2vkr_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2vkr ConSurf].
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<div style="clear:both"></div>
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===3FE-4S, 4FE-4S PLUS ZN ACIDIANUS AMBIVALENS FERREDOXIN===
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==See Also==
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*[[Ferredoxin 3D structures|Ferredoxin 3D structures]]
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__TOC__
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_18258200}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 18258200 is the PubMed ID number.
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{{ABSTRACT_PUBMED_18258200}}
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==About this Structure==
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2VKR is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Acidianus_ambivalens Acidianus ambivalens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VKR OCA].
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==Reference==
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Crystallographic analysis of the intact metal centres [3Fe-4S](1+/0) and [4Fe-4S](2+/1+) in a Zn(2+)-containing ferredoxin., Frazao C, Aragao D, Coelho R, Leal SS, Gomes CM, Teixeira M, Carrondo MA, FEBS Lett. 2008 Mar 5;582(5):763-7. Epub 2008 Feb 5. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18258200 18258200]
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A spectroscopic study of the temperature induced modifications on ferredoxin folding and iron-sulfur moieties., Todorovic S, Leal SS, Salgueiro CA, Zebger I, Hildebrandt P, Murgida DH, Gomes CM, Biochemistry. 2007 Sep 18;46(37):10733-8. Epub 2007 Aug 16. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17696500 17696500]
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Natural domain design: enhanced thermal stability of a zinc-lacking ferredoxin isoform shows that a hydrophobic core efficiently replaces the structural metal site., Rocha R, Leal SS, Teixeira VH, Regalla M, Huber H, Baptista AM, Soares CM, Gomes CM, Biochemistry. 2006 Aug 29;45(34):10376-84. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16922514 16922514]
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A seven-iron ferredoxin from the thermoacidophilic archaeon Desulfurolobus ambivalens., Teixeira M, Batista R, Campos AP, Gomes C, Mendes J, Pacheco I, Anemuller S, Hagen WR, Eur J Biochem. 1995 Jan 15;227(1-2):322-7. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/7851403 7851403]
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[[Category: Acidianus ambivalens]]
[[Category: Acidianus ambivalens]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Aragao, D.]]
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[[Category: Aragao D]]
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[[Category: Carrondo, M A.]]
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[[Category: Carrondo MA]]
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[[Category: Coelho, R.]]
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[[Category: Coelho R]]
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[[Category: Frazao, C.]]
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[[Category: Frazao C]]
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[[Category: Gomes, C M.]]
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[[Category: Gomes CM]]
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[[Category: Leal, S S.]]
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[[Category: Leal SS]]
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[[Category: Teixeira, M.]]
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[[Category: Teixeira M]]
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[[Category: 3fe-4]]
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[[Category: 4fe-4]]
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[[Category: Electron transport]]
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[[Category: Ferredoxin]]
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[[Category: Hemihedric twinnig]]
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[[Category: Iron]]
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[[Category: Iron-sulfur]]
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[[Category: Iron-sulfur protein]]
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[[Category: Metal-binding]]
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[[Category: Methylation]]
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[[Category: Protein folding]]
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[[Category: Thermophile]]
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[[Category: Thermostable protein]]
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[[Category: Transport]]
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[[Category: Zinc]]
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[[Category: Zn center]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 05:19:45 2008''
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Current revision

3Fe-4S, 4Fe-4S plus Zn Acidianus ambivalens ferredoxin

PDB ID 2vkr

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