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6g83
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 6g83 is ON HOLD Authors: Piton, J., Makarov, V., Cole, S.T. Description: Crystal structure of M. tuberculosis DprE1 in complex with sPBTZ169 (sulfo...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of M. tuberculosis DprE1 in complex with sPBTZ169 (sulfonylPBTZ)== | |
| - | + | <StructureSection load='6g83' size='340' side='right'caption='[[6g83]], [[Resolution|resolution]] 2.40Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6g83]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6G83 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6G83 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EQ8:[2-(4-cyclohexylsulfonylpiperazin-1-yl)-4-oxidanylidene-6-(trifluoromethyl)-1,3-benzothiazin-8-yl]-oxidanylidene-azanium'>EQ8</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene></td></tr> |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6g83 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6g83 OCA], [https://pdbe.org/6g83 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6g83 RCSB], [https://www.ebi.ac.uk/pdbsum/6g83 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6g83 ProSAT]</span></td></tr> |
| - | [[Category: | + | </table> |
| - | [[Category: Makarov | + | == Function == |
| + | [https://www.uniprot.org/uniprot/DPRE1_MYCTU DPRE1_MYCTU] Involved in the epimerization of decaprenylphosphoryl ribose (DPR) to decaprenylphosphoryl arabinose (DPA) a precursor for arabinan synthesis in mycobacterial cell wall biosynthesis. Probably catalyzes the oxidation at C-2 of decaprenylphosphoryl ribose (DPR) to yield decaprenylphosphoryl 2-keto-ribose (DPX).<ref>PMID:16291675</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Mycobacterium tuberculosis H37Rv]] | ||
| + | [[Category: Cole ST]] | ||
| + | [[Category: Makarov V]] | ||
| + | [[Category: Piton J]] | ||
Current revision
Crystal structure of M. tuberculosis DprE1 in complex with sPBTZ169 (sulfonylPBTZ)
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