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7az8
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 7az8 is ON HOLD Authors: Monsarrat, C., Compain, G., Andre, C., Martiel, I., Engilberge, S., Olieric, V., Wolff, P., Brillet, K., Landolfo, M., Silv...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==DNA polymerase sliding clamp from Escherichia coli with peptide 43 bound== | |
| + | <StructureSection load='7az8' size='340' side='right'caption='[[7az8]], [[Resolution|resolution]] 1.61Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[7az8]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_2-427-07_S4_C3 Escherichia coli 2-427-07_S4_C3] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7AZ8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7AZ8 FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.61Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1PE:PENTAETHYLENE+GLYCOL'>1PE</scene>, <scene name='pdbligand=2K8:(6R)-2-AMINO-4-OXO-3,4,5,6,7,8-HEXAHYDROPTERIDINE-6-CARBOXYLIC+ACID'>2K8</scene>, <scene name='pdbligand=ALC:2-AMINO-3-CYCLOHEXYL-PROPIONIC+ACID'>ALC</scene>, <scene name='pdbligand=GLN:GLUTAMINE'>GLN</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=TCA:PHENYLETHYLENECARBOXYLIC+ACID'>TCA</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7az8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7az8 OCA], [https://pdbe.org/7az8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7az8 RCSB], [https://www.ebi.ac.uk/pdbsum/7az8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7az8 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/DPO3B_ECOLI DPO3B_ECOLI] DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP-independent) along duplex DNA. | ||
| - | + | ==See Also== | |
| - | + | *[[DNA polymerase 3D structures|DNA polymerase 3D structures]] | |
| - | + | __TOC__ | |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: Andre | + | [[Category: Escherichia coli 2-427-07_S4_C3]] |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Synthetic construct]] |
| - | [[Category: | + | [[Category: Andre C]] |
| - | [[Category: | + | [[Category: Brillet K]] |
| - | [[Category: | + | [[Category: Burnouf DY]] |
| - | [[Category: | + | [[Category: Compain G]] |
| - | [[Category: | + | [[Category: Engilberge S]] |
| - | [[Category: | + | [[Category: Guichard G]] |
| - | [[Category: | + | [[Category: Landolfo M]] |
| - | [[Category: | + | [[Category: Martiel I]] |
| - | [[Category: | + | [[Category: Monsarrat C]] |
| - | [[Category: | + | [[Category: Olieric V]] |
| + | [[Category: Silva da Veiga C]] | ||
| + | [[Category: Wagner J]] | ||
| + | [[Category: Wolff P]] | ||
Current revision
DNA polymerase sliding clamp from Escherichia coli with peptide 43 bound
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