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7pcu
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 7pcu is ON HOLD Authors: Description: Category: Unreleased Structures) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of YTHDF1 YTH domain in complex with ebselen== | |
| - | + | <StructureSection load='7pcu' size='340' side='right'caption='[[7pcu]], [[Resolution|resolution]] 2.65Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[7pcu]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7PCU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7PCU FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.65Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=9JT:~{N}-phenyl-2-selanyl-benzamide'>9JT</scene></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7pcu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7pcu OCA], [https://pdbe.org/7pcu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7pcu RCSB], [https://www.ebi.ac.uk/pdbsum/7pcu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7pcu ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/YTHD1_HUMAN YTHD1_HUMAN] Specifically recognizes and binds N6-methyladenosine (m6A)-containing RNAs. M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in the efficiency of mRNA splicing, processing and stability.<ref>PMID:24284625</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Cazzanelli G]] | ||
| + | [[Category: Dalle Vedove A]] | ||
| + | [[Category: Lolli G]] | ||
| + | [[Category: Provenzani A]] | ||
| + | [[Category: Quattrone A]] | ||
Current revision
Crystal structure of YTHDF1 YTH domain in complex with ebselen
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