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7zho
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 7zho is ON HOLD Authors: Chaikuad, A., Axtman, A., Knapp, S., Structural Genomics Consortium (SGC) Description: Crystal structure of TTBK1 in compl...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of TTBK1 in complex with compound 3 (7-001)== | |
| - | + | <StructureSection load='7zho' size='340' side='right'caption='[[7zho]], [[Resolution|resolution]] 2.08Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[7zho]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7ZHO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7ZHO FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.08Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=IQR:4-[3-(2-azanylpyrimidin-4-yl)-1~{H}-indol-5-yl]-2-methyl-but-3-yn-2-ol'>IQR</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7zho FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7zho OCA], [https://pdbe.org/7zho PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7zho RCSB], [https://www.ebi.ac.uk/pdbsum/7zho PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7zho ProSAT]</span></td></tr> |
| - | [[Category: | + | </table> |
| - | [[Category: | + | == Function == |
| - | [[Category: | + | [https://www.uniprot.org/uniprot/TTBK1_HUMAN TTBK1_HUMAN] Serine/threonine kinase which is able to phosphorylate TAU on serine, threonine and tyrosine residues. Induces aggregation of TAU.<ref>PMID:16923168</ref> |
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Axtman A]] | ||
| + | [[Category: Chaikuad A]] | ||
| + | [[Category: Knapp S]] | ||
Current revision
Crystal structure of TTBK1 in complex with compound 3 (7-001)
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