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8b2a
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of type I dehydroquinase from Salmonella typhi inhibited by an epoxide derivative== | |
| - | + | <StructureSection load='8b2a' size='340' side='right'caption='[[8b2a]], [[Resolution|resolution]] 1.65Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8b2a]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8B2A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8B2A FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.65Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=PVI:(4R,5R)-3-amino-4,5-dihydroxy-cyclohexene-1-carboxylic+acid'>PVI</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8b2a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8b2a OCA], [https://pdbe.org/8b2a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8b2a RCSB], [https://www.ebi.ac.uk/pdbsum/8b2a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8b2a ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/AROD_STAAB AROD_STAAB] Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Staphylococcus aureus]] | ||
| + | [[Category: Gonzalez-Bello C]] | ||
| + | [[Category: Hawkins AR]] | ||
| + | [[Category: Lence E]] | ||
| + | [[Category: Maneiro M]] | ||
| + | [[Category: Otero JM]] | ||
| + | [[Category: Rodriguez A]] | ||
| + | [[Category: Thompson P]] | ||
| + | [[Category: Van Raaij MJ]] | ||
Current revision
Crystal structure of type I dehydroquinase from Salmonella typhi inhibited by an epoxide derivative
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