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8bdf
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| - | '''Unreleased structure''' | ||
| - | + | ==Tubulin-taxane-2a complex== | |
| + | <StructureSection load='8bdf' size='340' side='right'caption='[[8bdf]], [[Resolution|resolution]] 1.95Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[8bdf]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus], [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus] and [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8BDF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8BDF FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.95Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACP:PHOSPHOMETHYLPHOSPHONIC+ACID+ADENYLATE+ESTER'>ACP</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=R42:[(1~{S},2~{S},3~{R},4~{S},7~{R},9~{S},10~{S},12~{R},15~{S})-4-acetyloxy-15-[(2~{R},3~{S})-3-[(4-methoxy-2-methylidene-4-oxidanylidene-butanoyl)amino]-2-oxidanyl-3-phenyl-propanoyl]oxy-10,14,16,16-tetramethyl-1,9,12-tris(oxidanyl)-11-oxidanylidene-6-oxatetracyclo[11.3.1.0^{3,10}.0^{4,7}]heptadec-13-en-2-yl]+benzoate'>R42</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8bdf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8bdf OCA], [https://pdbe.org/8bdf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8bdf RCSB], [https://www.ebi.ac.uk/pdbsum/8bdf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8bdf ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/TBA1B_BOVIN TBA1B_BOVIN] Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. | ||
| - | + | ==See Also== | |
| - | + | *[[Stathmin-4 3D structures|Stathmin-4 3D structures]] | |
| - | + | *[[Tubulin 3D Structures|Tubulin 3D Structures]] | |
| - | [[Category: | + | __TOC__ |
| + | </StructureSection> | ||
| + | [[Category: Bos taurus]] | ||
| + | [[Category: Gallus gallus]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Rattus norvegicus]] | ||
| + | [[Category: Altmann KH]] | ||
| + | [[Category: Bargsten K]] | ||
| + | [[Category: Diaz JF]] | ||
| + | [[Category: Estevez-Gallego J]] | ||
| + | [[Category: Fang WS]] | ||
| + | [[Category: Gago F]] | ||
| + | [[Category: Gaillard N]] | ||
| + | [[Category: Kamimura S]] | ||
| + | [[Category: Li S]] | ||
| + | [[Category: Lucena-Agell D]] | ||
| + | [[Category: Ma Y]] | ||
| + | [[Category: Muehlethaler T]] | ||
| + | [[Category: Oliva MA]] | ||
| + | [[Category: Prota AE]] | ||
| + | [[Category: Steinmetz MO]] | ||
Current revision
Tubulin-taxane-2a complex
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Categories: Bos taurus | Gallus gallus | Large Structures | Rattus norvegicus | Altmann KH | Bargsten K | Diaz JF | Estevez-Gallego J | Fang WS | Gago F | Gaillard N | Kamimura S | Li S | Lucena-Agell D | Ma Y | Muehlethaler T | Oliva MA | Prota AE | Steinmetz MO
