This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
8c77
From Proteopedia
(Difference between revisions)
m (Protected "8c77" [edit=sysop:move=sysop]) |
|||
| (One intermediate revision not shown.) | |||
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Human cathepsin L after reaction with the thiocarbazate inhibitor CID 16725315== | |
| - | + | <StructureSection load='8c77' size='340' side='right'caption='[[8c77]], [[Resolution|resolution]] 1.70Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8c77]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8C77 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8C77 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene>, <scene name='pdbligand=TXH:~{tert}-butyl+~{N}-[(2~{S})-3-(1~{H}-indol-3-yl)-1-(2-methanoylhydrazinyl)-1-oxidanylidene-propan-2-yl]carbamate'>TXH</scene></td></tr> |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8c77 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8c77 OCA], [https://pdbe.org/8c77 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8c77 RCSB], [https://www.ebi.ac.uk/pdbsum/8c77 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8c77 ProSAT]</span></td></tr> |
| - | [[Category: | + | </table> |
| - | [[Category: | + | == Function == |
| - | [[Category: | + | [https://www.uniprot.org/uniprot/CATL1_HUMAN CATL1_HUMAN] Important for the overall degradation of proteins in lysosomes. |
| - | [[Category: | + | __TOC__ |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: | + | [[Category: Homo sapiens]] |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: Lindic | + | [[Category: Chapman HN]] |
| - | [[Category: | + | [[Category: Ewert W]] |
| - | [[Category: | + | [[Category: Falke S]] |
| - | [[Category: | + | [[Category: Guenther S]] |
| - | [[Category: | + | [[Category: Hinrichs W]] |
| - | [[Category: | + | [[Category: Karnicar K]] |
| + | [[Category: Lieske J]] | ||
| + | [[Category: Lindic N]] | ||
| + | [[Category: Loboda J]] | ||
| + | [[Category: Meents A]] | ||
| + | [[Category: Reinke PYA]] | ||
| + | [[Category: Sekirnik A]] | ||
| + | [[Category: Turk D]] | ||
| + | [[Category: Usenik A]] | ||
Current revision
Human cathepsin L after reaction with the thiocarbazate inhibitor CID 16725315
| |||||||||||
Categories: Homo sapiens | Large Structures | Chapman HN | Ewert W | Falke S | Guenther S | Hinrichs W | Karnicar K | Lieske J | Lindic N | Loboda J | Meents A | Reinke PYA | Sekirnik A | Turk D | Usenik A
