351d

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(New page: 200px<br /><applet load="351d" size="350" color="white" frame="true" align="right" spinBox="true" caption="351d, resolution 1.640&Aring;" /> '''X-RAY CRYSTAL STRUC...)
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[[Image:351d.gif|left|200px]]<br /><applet load="351d" size="350" color="white" frame="true" align="right" spinBox="true"
 
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caption="351d, resolution 1.640&Aring;" />
 
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'''X-RAY CRYSTAL STRUCTURES OF THE HEXAMER DCACGCG: CRYSTALS GROWN IN THE PRESENCE OF RUTHENIUM (II) HEXAMMINE CHLORIDE'''<br />
 
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==Overview==
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==X-RAY CRYSTAL STRUCTURES OF THE HEXAMER DCACGCG: CRYSTALS GROWN IN THE PRESENCE OF RUTHENIUM (II) HEXAMMINE CHLORIDE==
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Hexammine ions are strong inducers of the transition from the B-form to, the left-handed Z-form in DNA. Here the structure of d(CACGCG). d(CGCGTG), obtained from crystals grown from a drop containing [Ru(NH3)6]Cl3 is, reported. The structure is clearly characterized as Z-DNA. When compared, with the structure of d(CACGCG).d(CGCGTG)/MgCl2 and that of d(CGCGCG)2, subtle differences are seen, most noticeably in the water structure. Since, stable well diffracting crystals grow easily in the presence of, [Ru(NH3)6]Cl3 and since this ion is not visible in the electron density it, is concluded that the ion plays a non-specific role in stabilizing Z-DNA.
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<StructureSection load='351d' size='340' side='right'caption='[[351d]], [[Resolution|resolution]] 1.64&Aring;' scene=''>
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== Structural highlights ==
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==About this Structure==
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<table><tr><td colspan='2'>[[351d]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=351D OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=351D FirstGlance]. <br>
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351D is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/ ]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=351D OCA].
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.64&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=351d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=351d OCA], [https://pdbe.org/351d PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=351d RCSB], [https://www.ebi.ac.uk/pdbsum/351d PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=351d ProSAT]</span></td></tr>
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==Reference==
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</table>
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Structure of d(CACGCG).d(CGCGTG) in crystals grown in the presence of ruthenium III hexammine chloride., Karthe P, Gautham N, Acta Crystallogr D Biol Crystallogr. 1998 Jul 1;54(Pt 4):501-9. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=9761846 9761846]
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__TOC__
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[[Category: Protein complex]]
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</StructureSection>
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[[Category: Gautham, N.]]
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[[Category: Large Structures]]
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[[Category: Karthe, P.]]
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[[Category: Gautham N]]
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[[Category: double helix]]
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[[Category: Karthe P]]
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[[Category: z-dna]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jan 29 21:36:16 2008''
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Current revision

X-RAY CRYSTAL STRUCTURES OF THE HEXAMER DCACGCG: CRYSTALS GROWN IN THE PRESENCE OF RUTHENIUM (II) HEXAMMINE CHLORIDE

PDB ID 351d

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