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3ar4

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[[Image:3ar4.png|left|200px]]
 
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{{STRUCTURE_3ar4| PDB=3ar4 | SCENE= }}
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==Calcium pump crystal structure with bound ATP and TG in the absence of Ca2+==
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<StructureSection load='3ar4' size='340' side='right'caption='[[3ar4]], [[Resolution|resolution]] 2.15&Aring;' scene=''>
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===Calcium pump crystal structure with bound ATP and TG in the absence of Ca2+===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3ar4]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3AR4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3AR4 FirstGlance]. <br>
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{{ABSTRACT_PUBMED_21239683}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.15&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene>, <scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PTY:PHOSPHATIDYLETHANOLAMINE'>PTY</scene>, <scene name='pdbligand=TG1:OCTANOIC+ACID+[3S-[3ALPHA,+3ABETA,+4ALPHA,+6BETA,+6ABETA,+7BETA,+8ALPHA(Z),+9BALPHA]]-6-(ACETYLOXY)-2,3,-3A,4,5,6,6A,7,8,9B-DECAHYDRO-3,3A-DIHYDROXY-3,6,9-TRIMETHYL-8-[(2-METHYL-1-OXO-2-BUTENYL)OX+Y]-2-OXO-4-(1-OXOBUTOXY)-AZULENO[4,5-B]FURAN-7-YL+ESTER'>TG1</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ar4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ar4 OCA], [https://pdbe.org/3ar4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ar4 RCSB], [https://www.ebi.ac.uk/pdbsum/3ar4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ar4 ProSAT]</span></td></tr>
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[[3ar4]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3AR4 OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/AT2A1_RABIT AT2A1_RABIT] This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen. Contributes to calcium sequestration involved in muscular excitation/contraction (By similarity).
==See Also==
==See Also==
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*[[ATPase|ATPase]]
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*[[ATPase 3D structures|ATPase 3D structures]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:021239683</ref><references group="xtra"/>
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[[Category: Large Structures]]
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[[Category: Calcium-transporting ATPase]]
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[[Category: Oryctolagus cuniculus]]
[[Category: Oryctolagus cuniculus]]
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[[Category: Iwasawa, S.]]
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[[Category: Iwasawa S]]
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[[Category: Toyoshima, C.]]
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[[Category: Toyoshima C]]
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[[Category: Tsueda, J.]]
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[[Category: Tsueda J]]
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[[Category: Yonekura, S.]]
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[[Category: Yonekura S]]
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[[Category: Atp binding]]
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[[Category: Calcium binding]]
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[[Category: Calcium transport]]
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[[Category: Endoplasmic reticulum]]
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[[Category: Hydrolase]]
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[[Category: Hydrolase-hydrolase inhibitor complex]]
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[[Category: P-type atpase]]
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[[Category: Sarcoplasmic reticulum]]
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Current revision

Calcium pump crystal structure with bound ATP and TG in the absence of Ca2+

PDB ID 3ar4

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