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5qmg
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 5qmg is ON HOLD Authors: Ilyichova, O.V., Bentley, M.R., Doak, B.C., Scanlon, M.J. Description: Group deposition of library data -Crystal Structure...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Group deposition of library data - Crystal Structure of EcDsbA after initial refinement with no ligand modelled (structure F10_1)== | |
| - | + | <StructureSection load='5qmg' size='340' side='right'caption='[[5qmg]], [[Resolution|resolution]] 2.11Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5qmg]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5QMG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5QMG FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.109Å</td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5qmg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5qmg OCA], [https://pdbe.org/5qmg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5qmg RCSB], [https://www.ebi.ac.uk/pdbsum/5qmg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5qmg ProSAT]</span></td></tr> |
| - | [[Category: | + | </table> |
| - | [[Category: | + | == Function == |
| - | [[Category: | + | [https://www.uniprot.org/uniprot/DSBA_ECOLI DSBA_ECOLI] Required for disulfide bond formation in some periplasmic proteins such as PhoA or OmpA. Acts by transferring its disulfide bond to other proteins and is reduced in the process. DsbA is reoxidized by DsbB. Required for pilus biogenesis. PhoP-regulated transcription is redox-sensitive, being activated when the periplasm becomes more reducing (deletion of dsbA/dsbB, treatment with dithiothreitol). MgrB acts between DsbA/DsbB and PhoP/PhoQ in this pathway.<ref>PMID:1429594</ref> <ref>PMID:22267510</ref> |
| - | [[Category: | + | == References == |
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Escherichia coli K-12]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Bentley MR]] | ||
| + | [[Category: Doak BC]] | ||
| + | [[Category: Ilyichova OV]] | ||
| + | [[Category: Scanlon MJ]] | ||
Current revision
Group deposition of library data - Crystal Structure of EcDsbA after initial refinement with no ligand modelled (structure F10_1)
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