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Nucleoprotein 3D structures

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Current revision (10:57, 7 February 2024) (edit) (undo)
 
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Line 9: Line 9:
**[[1yvr]] – XlNP Ro – ''Xenopus laevis''<br />
**[[1yvr]] – XlNP Ro – ''Xenopus laevis''<br />
**[[3ouo]], [[3ov9]] – NP – Rift valley fever virus<br />
**[[3ouo]], [[3ov9]] – NP – Rift valley fever virus<br />
-
**[[3q7b]], [[3q7c]] – LvNP exonuclease domain – Lassa virus<br />
+
**[[3q7b]], [[3q7c]], [[7v37]] – LvNP exonuclease domain 342-569 – Lassa virus<br />
**[[3mwp]], [[3mwt]], [[3r3l]] – LvNP<br />
**[[3mwp]], [[3mwt]], [[3r3l]] – LvNP<br />
 +
**[[7v3a]] – LvNP (mutant)<br />
**[[3pto]] - VvNP – Vesicular stomatitis Indiana virus<br />
**[[3pto]] - VvNP – Vesicular stomatitis Indiana virus<br />
**[[2qvj]] – VvNP (mutant)<br />
**[[2qvj]] – VvNP (mutant)<br />
 +
**[[7umk]], [[7uml]], [[7uws]] - VvNP – Cryo EM<br />
**[[5e04]] - AvNP – Andes virus<br />
**[[5e04]] - AvNP – Andes virus<br />
**[[2k48]] – AvNP N terminal - NMR<br />
**[[2k48]] – AvNP N terminal - NMR<br />
**[[6g13]] - McvNP C terminal – MERS coronavirus<br />
**[[6g13]] - McvNP C terminal – MERS coronavirus<br />
**[[6kl2]] - McvNP N terminal <br />
**[[6kl2]] - McvNP N terminal <br />
 +
**[[7n45]] - NP C terminal – HKU1 coronavirus<br />
**[[3hd4]] – NP N terminal – Murine hepatitis virus<br />
**[[3hd4]] – NP N terminal – Murine hepatitis virus<br />
**[[2wfs]], [[2ymn]], [[6i54]], [[6i7b]], [[6i7m]], [[6i85]] – IvNP – Cryo EM – Influenza virus<br />
**[[2wfs]], [[2ymn]], [[6i54]], [[6i7b]], [[6i7m]], [[6i85]] – IvNP – Cryo EM – Influenza virus<br />
-
**[[3zdp]], [[4dyt]] – IvNP (mutant)<br />
+
**[[3zdp]], [[4dyt]], [[7nt8]] – IvNP (mutant)<br />
**[[2q06]], [[2iqh]], [[3tj0]], [[4dys]], [[4iry]], [[5b7b]], [[5n2u]] – IvNP<br />
**[[2q06]], [[2iqh]], [[3tj0]], [[4dys]], [[4iry]], [[5b7b]], [[5n2u]] – IvNP<br />
**[[6ehl]] - EvNP – Zaire Ebola virus – Cryo EM<br />
**[[6ehl]] - EvNP – Zaire Ebola virus – Cryo EM<br />
Line 49: Line 52:
**[[6yjl]] – RsvNP C terminal - NMR<br />
**[[6yjl]] – RsvNP C terminal - NMR<br />
**[[6ydr]] - NP C terminal - Mengla dianlovirus<br />
**[[6ydr]] - NP C terminal - Mengla dianlovirus<br />
 +
**[[8fwl]] - NP – Lyssavirus australis<br />
 +
**[[7xpn]] - SvcNP – Sprivirus cyprinus<br />
 +
**[[7aoy]] – BvNP – Bunyamwera virus – Cryo EM<br />
 +
**[[7xiv]] - LcvNP – Lloviu cuevavirus <br />
*Nucleoprotein complex with RNA
*Nucleoprotein complex with RNA
Line 58: Line 65:
**[[3hhz]] - VvNP + phosphoprotein + RNA<br />
**[[3hhz]] - VvNP + phosphoprotein + RNA<br />
**[[2wj8]], [[2yhm]], [[4bkk]] – RsvNP + RNA <br />
**[[2wj8]], [[2yhm]], [[4bkk]] – RsvNP + RNA <br />
-
**[[2gtt]] – NP + RNA – Rabies virus<br />
+
**[[2gtt]], [[8ffr]] – RvNP + RNA – Rabies virus<br />
**[[1wwg]], [[1wwd]], [[1wwe]], [[1u6p]] - MvNP P10 + RNA – NMR<br />
**[[1wwg]], [[1wwd]], [[1wwe]], [[1u6p]] - MvNP P10 + RNA – NMR<br />
**[[7dkg]], [[7dxp]] - IvNP + RNA <br />
**[[7dkg]], [[7dxp]] - IvNP + RNA <br />
Line 78: Line 85:
**[[6m7d]] - NP + RNA – Sendai virus – Cryo EM<br />
**[[6m7d]] - NP + RNA – Sendai virus – Cryo EM<br />
**[[6jc3]] - NP + RNA – Avian orthoavulavirus – Cryo EM<br />
**[[6jc3]] - NP + RNA – Avian orthoavulavirus – Cryo EM<br />
 +
**[[7ypw]], [[7yr8]] - LcvNP + RNA – Cryo EM<br />
 +
**[[7f1m]] - LvmvNP + RNA – Cryo EM<br />
 +
**[[7yg7]] - SvcNP + RNA – Cryo EM<br />
*Nucleoprotein complex with antibody
*Nucleoprotein complex with antibody
Line 92: Line 102:
**[[3mx2]], [[3mx5]] – LvNP + nucleotide<br />
**[[3mx2]], [[3mx5]] – LvNP + nucleotide<br />
 +
**[[7v38]], [[7v39]] - LvNP + inhibitor <br />
 +
**[[7v3b]], [[7v3c]] - LvNP (mutant) + inhibitor <br />
**[[2wyy]] – VvNP + poly U – Cryo EM<br />
**[[2wyy]] – VvNP + poly U – Cryo EM<br />
**[[3hhw]], [[3pmk]] – VvNP + phosphoprotein<br />r />
**[[3hhw]], [[3pmk]] – VvNP + phosphoprotein<br />r />
**[[4co6]] - NvNP + phosphoprotein – Nipah virus<br />
**[[4co6]] - NvNP + phosphoprotein – Nipah virus<br />
 +
**[[8b8v]] - RvNP + phosphoprotein <br />
**[[7ev8]] - NP + phosphoprotein – Human respirovirus<br />
**[[7ev8]] - NP + phosphoprotein – Human respirovirus<br />
**[[4ucc]] – RsvNP N terminal + inhibitor<br />
**[[4ucc]] – RsvNP N terminal + inhibitor<br />
Line 109: Line 122:
**[[5fvd]] - HmpvNP + phosphoprotein<br />
**[[5fvd]] - HmpvNP + phosphoprotein<br />
**[[5wkn]] - PivNP + phosphoprotein<br />
**[[5wkn]] - PivNP + phosphoprotein<br />
-
**[[6kl5]], [[6kl6]], [[6lnn]], [[6lz6]], [[6lz8]] – McvNP N terminal + inhibitor<br />
+
**[[6kl5]], [[6kl6]], [[6lnn]], [[6lz6]], [[6lz8]], [[7dyd]] – McvNP N terminal + inhibitor<br />
*Nucleoprotein from SARS-Covid 2
*Nucleoprotein from SARS-Covid 2
-
**[[6vyo]], [[6wkp]], [[6yi3]], [[7cdz]], [[4j3k]], [[5n4k]], [[2ofz]], [[2og3]], [[6m3m]], [[7cdz]], [[7vnu]] - ScvNP N terminal 45-181 – SARS coronavirus 2<br />
+
**[[8fd5]], [[8fg2]] - ScvNP 1-419 – SARS coronavirus 2 – Cryo EM<br />
-
**[[1ssk]] - ScvNP N terminal – NMR<br />
+
**[[6vyo]], [[6wkp]], [[6yi3]], [[7cdz]], [[4j3k]], [[5n4k]], [[2ofz]], [[2og3]], [[6m3m]], [[7cdz]], [[7uw3]], [[7vbd]], [[7vbf]], [[7vnu]], [[7xx1]] - ScvNP N terminal 45-181 <br />
-
**[[6wji]], [[6wzo]], [[6wzq]], [[6yun]], [[6zco]], [[7c22]], [[7ce0]], [[5epw]], [[2gib]], [[7c22]], [[7de1]], [[7f2b]], [[7f2e]] - ScvNP C terminal dimerization domain 257-364 <br />
+
**[[1ssk]], [[7sd4]] - ScvNP N terminal – NMR<br />
-
**[[2jw8]] - ScvNP C terminal dimerization domain - NMR <br />
+
**[[7acs]], [[7act]] - ScvNP N terminal + RNA - NMR<br />
**[[7acs]], [[7act]] - ScvNP N terminal + RNA - NMR<br />
-
**[[7cr5]], [[7n3c]], [[7n3d]] - ScvNP N-terminal + antibody <br />
+
**[[7cr5]], [[7n3c]], [[7n3d]], [[7str]], [[7sts]], [[7sue]] - ScvNP N-terminal + antibody <br />
**[[7n0r]], [[7r98]] – ScvNP N-terminal + nanobody <br />
**[[7n0r]], [[7r98]] – ScvNP N-terminal + nanobody <br />
-
**[[7n0i]] – ScvNP C-terminal + nanobody <br />
 
**[[4kxj]] – ScvNP N terminal + PJ34 <br />
**[[4kxj]] – ScvNP N terminal + PJ34 <br />
-
**[[4li4]], [[4lm7]], [[4lm9]], [[4lmc]] – ScvNP N terminal + nucleotide <br />
+
**[[4li4]], [[4lm7]], [[4lm9]], [[4lmc]], [[7o35]], [[7o36]], [[7xxk]] – ScvNP N terminal + nucleotide <br />
**[[4lmt]] – ScvNP N terminal + quinoline derivative <br />
**[[4lmt]] – ScvNP N terminal + quinoline derivative <br />
-
 
+
**[[6wji]], [[6wzo]], [[6wzq]], [[6yun]], [[6zco]], [[7c22]], [[7ce0]], [[5epw]], [[2gib]], [[7c22]], [[7de1]], [[7f2b]], [[7f2e]], [[7o05]], [[7uxx]], [[7vbe]], [[7xwx]] - ScvNP C terminal dimerization domain 257-364 <br />
 +
**[[2jw8]] - ScvNP C terminal dimerization domain - NMR <br />
 +
**[[7n0i]] – ScvNP C-terminal + nanobody <br />
 +
**[[7uxz]] – ScvNP C-terminal + chicoric acid <br />
*'''Ribonucleoprotein'''
*'''Ribonucleoprotein'''
Line 132: Line 146:
**[[4h5l]], [[4csg]], [[5fva]] – TvRNP – Toscana virus<br />
**[[4h5l]], [[4csg]], [[5fva]] – TvRNP – Toscana virus<br />
**[[4csf]] – TvRNP + RNA<br />
**[[4csf]] – TvRNP + RNA<br />
 +
**[[8rcq]] – TvRNP + nanobody<br />
**[[4uft]] – MevRNP + RNA <br />
**[[4uft]] – MevRNP + RNA <br />
Line 137: Line 152:
**[[2a3j]], [[1fht]] - h-snRNP U1 A RRM – human - NMR<br />
**[[2a3j]], [[1fht]] - h-snRNP U1 A RRM – human - NMR<br />
 +
**[[7lhx]] - h-snRNP U1 A (mutant) <br />
**[[2u1a]] - h-snRNP U1 A RRM (mutant) – NMR<br />
**[[2u1a]] - h-snRNP U1 A RRM (mutant) – NMR<br />
**[[1dz5]] - h-snRNP U1 A (mutant) – NMR<br />
**[[1dz5]] - h-snRNP U1 A (mutant) – NMR<br />
**[[1oia]] - h-snRNP U1 A RRM<br />
**[[1oia]] - h-snRNP U1 A RRM<br />
 +
**[[7aep]] - h-snRNP U1 A RRM2 190-282 – NMR<br />
**[[2l5i]], [[2l5j]] - h-snRNP U1 70kDa residues 131-151 – NMR<br />
**[[2l5i]], [[2l5j]] - h-snRNP U1 70kDa residues 131-151 – NMR<br />
**[[2vy4]], [[2vy5]] - h-snRNP U11/U12 – NMR<br />
**[[2vy4]], [[2vy5]] - h-snRNP U11/U12 – NMR<br />
Line 157: Line 174:
**[[4wzj]] – h-snRNP U4 core domain<br />
**[[4wzj]] – h-snRNP U4 core domain<br />
**[[3p49]] - h-snRNP A RRM + glycine riboswitch RNA<br />
**[[3p49]] - h-snRNP A RRM + glycine riboswitch RNA<br />
-
**[[3iwn]] - h-snRNP U1 A RRM (mutant) + riboswitch RNA<br />
+
**[[3iwn]], [[7d7v]] - h-snRNP U1 A RRM (mutant) + riboswitch RNA<br />
**[[3pgw]], [[3mum]], [[3mur]], [[3mut]], [[3muv]], [[3egz]] - h-snRNP U1 A + DNA riboswitch<br />
**[[3pgw]], [[3mum]], [[3mur]], [[3mut]], [[3muv]], [[3egz]] - h-snRNP U1 A + DNA riboswitch<br />
**[[3mxh]], [[3irw]] - h-snRNP U1 A (mutant) + DNA riboswitch<br />
**[[3mxh]], [[3irw]] - h-snRNP U1 A (mutant) + DNA riboswitch<br />
Line 176: Line 193:
**[[3cul]], [[3cun]] - h-snRNP U1 A (mutant) + aminoacyl-tRNA synthetase ribozyme<br />
**[[3cul]], [[3cun]] - h-snRNP U1 A (mutant) + aminoacyl-tRNA synthetase ribozyme<br />
**[[2ozb]], [[3siu]], [[3siv]] - h-snRNP U4/U6 + NHP2-like protein + RNA<br />
**[[2ozb]], [[3siu]], [[3siv]] - h-snRNP U4/U6 + NHP2-like protein + RNA<br />
 +
**[[7px3]] - h-snRNP U5 + PRP8 + TSSC4 = Cryo EM<br />
**[[2bn5]] - Dm-snRNP U1 70kDa + PSI B box – NMR<br />
**[[2bn5]] - Dm-snRNP U1 70kDa + PSI B box – NMR<br />
**[[6f4h]] - Dm-snRNP U1 A + U1-SL2<br />
**[[6f4h]] - Dm-snRNP U1 A + U1-SL2<br />
Line 185: Line 203:
**[[3cw1]] - h-snRNP U1 in spliceosome<br />
**[[3cw1]] - h-snRNP U1 in spliceosome<br />
-
**[[5o9z]], [[5z58]], [[6ah0]], [[6ff7]], [[6icz]], [[6id0]], [[6id1]] - h-snRNP in spliceosome – Cryo EM<br />
+
**[[5o9z]], [[5z58]], [[6ah0]], [[6ff7]], [[6icz]], [[6id0]], [[6id1]], [[7a5p]], [[7aav]], [[7abf]], [[7abg]], [[7abi]], [[7dvq]], [[7qtt]], [[7vpx]], [[7w5b]], [[8c6j]], [[8ch6]], [[8hk1]] - h-snRNP in spliceosome – Cryo EM<br />
**[[5xjq]], [[5xjr]], [[5xjs]], [[5xjt]], [[5xju]], [[5xjl]] - h-snRNP in SMN<br />
**[[5xjq]], [[5xjr]], [[5xjs]], [[5xjt]], [[5xju]], [[5xjl]] - h-snRNP in SMN<br />
**[[4m77]], [[4m78]], [[4m7a]], [[4m7d]] - h-snRNP in LSM8 assembly<br />
**[[4m77]], [[4m78]], [[4m7a]], [[4m7d]] - h-snRNP in LSM8 assembly<br />
**[[6v4x]] - h-snRNP in pre-mRNA 3’-end processing – Cryo EM<br />
**[[6v4x]] - h-snRNP in pre-mRNA 3’-end processing – Cryo EM<br />
-
**[[6y53]], [[6y5q]] - h-snRNP in 17S U2 snRNP – Cryo EM<br />
+
**[[7w59]] - h-snRNP in pre-C*-I complex – Cryo EM<br />
 +
**[[7w5a]] - h-snRNP in pre-C*-II complex – Cryo EM<br />
 +
**[[7b0y]] - h-snRNP in RNA polymerase II-U1 complex – Cryo EM<br />
 +
**[[6y53]], [[6y5q]], [[7evo]] - h-snRNP in 17S U2 snRNP – Cryo EM<br />
**[[4f7u]] - m-snRNP in 8S assembly<br />
**[[4f7u]] - m-snRNP in 8S assembly<br />
-
**[[5wsg]], [[5y88]], [[5ylz]], [[5zwn]], [[5zwo]], [[6bk8]], [[6exn]], [[6g90]], [[6j6g]], [[6j6h]], [[6j6n]], [[6j6q]], [[6n7p]], [[6n7r]], [[6n7x]] - y-snRNP in spliceosome – Cryo EM<br />
+
**[[5wsg]], [[5y88]], [[5ylz]], [[5zwn]], [[5zwo]], [[6bk8]], [[6exn]], [[6g90]], [[6j6g]], [[6j6h]], [[6j6n]], [[6j6q]], [[6n7p]], [[6n7r]], [[6n7x]], [[7b9v]], [[7dco]], [[7oqc]], [[7oqe]] - y-snRNP in spliceosome – Cryo EM<br />
*'''Heterogenous nuclear ribonucleoprotein'''; Human domains – RRM1 10-93; RRM2 94-194; KH3 385-463; RRM3 654-729
*'''Heterogenous nuclear ribonucleoprotein'''; Human domains – RRM1 10-93; RRM2 94-194; KH3 385-463; RRM3 654-729
**[[1ha1]], [[1l3k]], [[1up1]] - h-hnRNP A1 RRM1-2<br />
**[[1ha1]], [[1l3k]], [[1up1]] - h-hnRNP A1 RRM1-2<br />
 +
**[[7zj2]] - h-hnRNP A1 1-320 – Cryo EM<br />
 +
**[[7bx7]] - h-hnRNP A1 188-320 – Cryo EM<br />
**[[2lyv]] - h-hnRNP A1 RRM 1-2 – NMR<br />
**[[2lyv]] - h-hnRNP A1 RRM 1-2 – NMR<br />
**[[2up1]] - h-hnRNP A1 RRM 1-2 + DNA<br />
**[[2up1]] - h-hnRNP A1 RRM 1-2 + DNA<br />
Line 203: Line 226:
**[[1wf2]] - h-hnRNP C1/C2 RRM1 – NMR<br />
**[[1wf2]] - h-hnRNP C1/C2 RRM1 – NMR<br />
**[[1hd0]], [[1hd1]], [[1iqt]] - h-hnRNP D0 RRM2 – NMR<br />
**[[1hd0]], [[1hd1]], [[1iqt]] - h-hnRNP D0 RRM2 – NMR<br />
 +
**[[7zir]] - h-hnRNP DL – Cryo EM<br />
**[[2hgl]], [[2hgm]], [[2hgn]] - h-hnRNP F QRRM1 – NMR<br />
**[[2hgl]], [[2hgm]], [[2hgn]] - h-hnRNP F QRRM1 – NMR<br />
**[[1wg5]], [[1wez]], [[2lxu]] - h-hnRNP H RRM1 – NMR<br />
**[[1wg5]], [[1wez]], [[2lxu]] - h-hnRNP H RRM1 – NMR<br />
 +
**[[7zug]] - h-hnRNP H1 RRM2 <br />
 +
**[[6dg1]] - h-hnRNP H2 RRM2 – NMR<br />
 +
**[[6dhs]] - h-hnRNP H2 RRM1-2<br />
**[[2ad9]], [[2adb]], [[2adc]] - h-hnRNP I – NMR<br />
**[[2ad9]], [[2adb]], [[2adc]] - h-hnRNP I – NMR<br />
**[[1zzk]] - h-hnRNP K KH3 domain<br />
**[[1zzk]] - h-hnRNP K KH3 domain<br />
Line 225: Line 252:
**[[1pgz]], [[1po6]] - h-hnRNP A1 RRM1-2+ DNA + inhibitor<br />
**[[1pgz]], [[1po6]] - h-hnRNP A1 RRM1-2+ DNA + inhibitor<br />
**[[1wtb]], [[1x0f]] - h-hnRNP D0 CTD 181-259 + DNA – NMR<br />
**[[1wtb]], [[1x0f]] - h-hnRNP D0 CTD 181-259 + DNA – NMR<br />
-
**[[6dg1]] - h-hnRNP H2 RRM2 – NMR<br />
+
**[[8sgh]] - h-hnRNP H2 103-225 + transportin<br />
-
**[[6dhs]] - h-hnRNP H2 RRM1-2<br />
+
**[[1zzi]], [[1zzj]], [[7cre]], [[7oqb]] - h-hnRNP K KH3 domain + DNA<br />
-
**[[1zzi]], [[1zzj]] - h-hnRNP K KH3 domain + DNA<br />
+
**[[1j5k]] - h-hnRNP K KH3 domain + DNA – NMR<br />
-
**[[1j5k]] - h-hnRNP K KH3 domain + DNA – NMR
+
**[[7cru]] - h-hnRNP K + importin<br />
 +
**[[7evr]], [[7evs]] - h-hnRNP L RRM2+ SETD2<br />
}}
}}
[[Category:Topic Page]]
[[Category:Topic Page]]

Current revision

3D Structures of Nucleoprotein

Updated on 07-February-2024

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Jaime Prilusky, Joel L. Sussman

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