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1cg2

From Proteopedia

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{{Seed}}
 
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[[Image:1cg2.png|left|200px]]
 
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==CARBOXYPEPTIDASE G2==
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The line below this paragraph, containing "STRUCTURE_1cg2", creates the "Structure Box" on the page.
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<StructureSection load='1cg2' size='340' side='right'caption='[[1cg2]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1cg2]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_sp._RS-16 Pseudomonas sp. RS-16]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1CG2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1CG2 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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{{STRUCTURE_1cg2| PDB=1cg2 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1cg2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1cg2 OCA], [https://pdbe.org/1cg2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1cg2 RCSB], [https://www.ebi.ac.uk/pdbsum/1cg2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1cg2 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/CBPG_PSES6 CBPG_PSES6] Catalyzes the hydrolysis of reduced and non-reduced folates to pteroates and L-glutamate. This enzyme has a broad specificity.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cg/1cg2_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1cg2 ConSurf].
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<div style="clear:both"></div>
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===CARBOXYPEPTIDASE G2===
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==See Also==
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*[[Carboxypeptidase 3D structures|Carboxypeptidase 3D structures]]
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__TOC__
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<!--
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_9083113}}, adds the Publication Abstract to the page
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[[Category: Large Structures]]
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(as it appears on PubMed at http://www.pubmed.gov), where 9083113 is the PubMed ID number.
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[[Category: Pseudomonas sp. RS-16]]
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[[Category: Blow DM]]
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{{ABSTRACT_PUBMED_9083113}}
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[[Category: Brick P]]
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[[Category: Melton RG]]
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==About this Structure==
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[[Category: Pauptit RA]]
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1CG2 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Pseudomonas_sp. Pseudomonas sp.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1CG2 OCA].
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[[Category: Rowsell S]]
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[[Category: Tucker AD]]
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==Reference==
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Crystal structure of carboxypeptidase G2, a bacterial enzyme with applications in cancer therapy., Rowsell S, Pauptit RA, Tucker AD, Melton RG, Blow DM, Brick P, Structure. 1997 Mar 15;5(3):337-47. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9083113 9083113]
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[[Category: Glutamate carboxypeptidase]]
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[[Category: Pseudomonas sp.]]
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[[Category: Single protein]]
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[[Category: Blow, D M.]]
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[[Category: Brick, P.]]
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[[Category: Melton, R G.]]
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[[Category: Pauptit, R A.]]
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[[Category: Rowsell, S.]]
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[[Category: Tucker, A D.]]
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[[Category: Hydrolase]]
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[[Category: Metallocarboxypeptidase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jun 30 20:42:09 2008''
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Current revision

CARBOXYPEPTIDASE G2

PDB ID 1cg2

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