This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1lcw

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (07:32, 14 February 2024) (edit) (undo)
 
(12 intermediate revisions not shown.)
Line 1: Line 1:
-
{{Seed}}
 
-
[[Image:1lcw.png|left|200px]]
 
-
<!--
+
==streptavidin-homobiotin complex==
-
The line below this paragraph, containing "STRUCTURE_1lcw", creates the "Structure Box" on the page.
+
<StructureSection load='1lcw' size='340' side='right'caption='[[1lcw]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[1lcw]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_avidinii Streptomyces avidinii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LCW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1LCW FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
-
-->
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SHM:HOMOBIOTIN'>SHM</scene></td></tr>
-
{{STRUCTURE_1lcw| PDB=1lcw | SCENE= }}
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1lcw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1lcw OCA], [https://pdbe.org/1lcw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1lcw RCSB], [https://www.ebi.ac.uk/pdbsum/1lcw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1lcw ProSAT]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/SAV_STRAV SAV_STRAV] The biological function of streptavidin is not known. Forms a strong non-covalent specific complex with biotin (one molecule of biotin per subunit of streptavidin).
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/lc/1lcw_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1lcw ConSurf].
 +
<div style="clear:both"></div>
-
===streptavidin-homobiotin complex===
+
==See Also==
-
 
+
*[[Avidin 3D structures|Avidin 3D structures]]
-
 
+
__TOC__
-
<!--
+
</StructureSection>
-
The line below this paragraph, {{ABSTRACT_PUBMED_12055191}}, adds the Publication Abstract to the page
+
[[Category: Large Structures]]
-
(as it appears on PubMed at http://www.pubmed.gov), where 12055191 is the PubMed ID number.
+
-
-->
+
-
{{ABSTRACT_PUBMED_12055191}}
+
-
 
+
-
==About this Structure==
+
-
1LCW is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Streptomyces_avidinii Streptomyces avidinii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LCW OCA].
+
-
 
+
-
==Reference==
+
-
Ligand exchange between proteins. Exchange of biotin and biotin derivatives between avidin and streptavidin., Pazy Y, Kulik T, Bayer EA, Wilchek M, Livnah O, J Biol Chem. 2002 Aug 23;277(34):30892-900. Epub 2002 Jun 7. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12055191 12055191]
+
-
[[Category: Single protein]]
+
[[Category: Streptomyces avidinii]]
[[Category: Streptomyces avidinii]]
-
[[Category: Bayer, E A.]]
+
[[Category: Bayer EA]]
-
[[Category: Livnah, O.]]
+
[[Category: Livnah O]]
-
[[Category: Pazy, Y.]]
+
[[Category: Pazy Y]]
-
[[Category: Wilchek, M.]]
+
[[Category: Wilchek M]]
-
[[Category: Avidin]]
+
-
[[Category: Biotin]]
+
-
[[Category: High affinity system]]
+
-
[[Category: Ligand exchange]]
+
-
[[Category: Streptavidin]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 2 12:24:36 2008''
+

Current revision

streptavidin-homobiotin complex

PDB ID 1lcw

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1lcw"
Personal tools