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1ln4

From Proteopedia

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[[Image:1ln4.jpg|left|200px]]<br /><applet load="1ln4" size="350" color="white" frame="true" align="right" spinBox="true"
 
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caption="1ln4, resolution 1.5&Aring;" />
 
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'''CRYSTAL STRUCTURE OF E. COLI YHBY'''<br />
 
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==Overview==
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==CRYSTAL STRUCTURE OF E. COLI YHBY==
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E. coli YhbY belongs to a conserved family of hypothetical proteins represented in eubacteria, archaea, and plants (Pfam code UPF0044). Three maize proteins harboring UPF0044-like domains are required for chloroplast group II intron splicing, and bioinformatic data suggest a role for prokaryotic UPF0044 members in translation. The crystal structure of YhbY has been determined. YhbY has a fold similar to that of the C-terminal domain of translation initiation factor 3 (IF3C), which binds to 16S rRNA in the 30S ribosome. Modeling studies indicate that the same surface is highly basic in all members of UPF0044, suggesting a conserved RNA binding surface. Taken together, the evidence suggests that members of UPF0044 constitute a previously unrecognized class of RNA binding domain.
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<StructureSection load='1ln4' size='340' side='right'caption='[[1ln4]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
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== Structural highlights ==
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==About this Structure==
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<table><tr><td colspan='2'>[[1ln4]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LN4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1LN4 FirstGlance]. <br>
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1LN4 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LN4 OCA].
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ln4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ln4 OCA], [https://pdbe.org/1ln4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ln4 RCSB], [https://www.ebi.ac.uk/pdbsum/1ln4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ln4 ProSAT]</span></td></tr>
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==Reference==
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</table>
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Crystal structure of E. coli YhbY: a representative of a novel class of RNA binding proteins., Ostheimer GJ, Barkan A, Matthews BW, Structure. 2002 Nov;10(11):1593-601. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=12429100 12429100]
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== Function ==
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[https://www.uniprot.org/uniprot/YHBY_ECOLI YHBY_ECOLI]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ln/1ln4_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ln4 ConSurf].
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<div style="clear:both"></div>
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__TOC__
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</StructureSection>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Barkan, A.]]
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[[Category: Barkan A]]
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[[Category: Matthews, B W.]]
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[[Category: Matthews BW]]
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[[Category: Ostheimer, G J.]]
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[[Category: Ostheimer GJ]]
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[[Category: putative rna-binding protein; putative translation factor]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 13:46:28 2008''
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Current revision

CRYSTAL STRUCTURE OF E. COLI YHBY

PDB ID 1ln4

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