This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.


Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1los

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
m (Protected "1los" [edit=sysop:move=sysop])
Current revision (07:34, 14 February 2024) (edit) (undo)
 
(8 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:1los.png|left|200px]]
 
-
<!--
+
==crystal structure of orotidine monophosphate decarboxylase mutant deltaR203A complexed with 6-azaUMP==
-
The line below this paragraph, containing "STRUCTURE_1los", creates the "Structure Box" on the page.
+
<StructureSection load='1los' size='340' side='right'caption='[[1los]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[1los]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Methanothermobacter_thermautotrophicus_str._Delta_H Methanothermobacter thermautotrophicus str. Delta H]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LOS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1LOS FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
-
-->
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=UP6:6-AZA+URIDINE+5-MONOPHOSPHATE'>UP6</scene></td></tr>
-
{{STRUCTURE_1los| PDB=1los | SCENE= }}
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1los FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1los OCA], [https://pdbe.org/1los PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1los RCSB], [https://www.ebi.ac.uk/pdbsum/1los PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1los ProSAT]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/PYRF_METTH PYRF_METTH] Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).[HAMAP-Rule:MF_01200_A]
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/lo/1los_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1los ConSurf].
 +
<div style="clear:both"></div>
-
===crystal structure of orotidine monophosphate decarboxylase mutant deltaR203A complexed with 6-azaUMP===
+
==See Also==
-
 
+
*[[Uridine 5'-monophosphate synthase 3D structures|Uridine 5'-monophosphate synthase 3D structures]]
-
 
+
__TOC__
-
<!--
+
</StructureSection>
-
The line below this paragraph, {{ABSTRACT_PUBMED_12011084}}, adds the Publication Abstract to the page
+
[[Category: Large Structures]]
-
(as it appears on PubMed at http://www.pubmed.gov), where 12011084 is the PubMed ID number.
+
[[Category: Methanothermobacter thermautotrophicus str. Delta H]]
-
-->
+
[[Category: Pai EF]]
-
{{ABSTRACT_PUBMED_12011084}}
+
[[Category: Wu N]]
-
 
+
-
==About this Structure==
+
-
[[1los]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Methanothermobacter_thermautotrophicus_str._delta_h Methanothermobacter thermautotrophicus str. delta h]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LOS OCA].
+
-
 
+
-
==Reference==
+
-
<ref group="xtra">PMID:12011084</ref><references group="xtra"/>
+
-
[[Category: Methanothermobacter thermautotrophicus str. delta h]]
+
-
[[Category: Orotidine-5'-phosphate decarboxylase]]
+
-
[[Category: Pai, E F.]]
+
-
[[Category: Wu, N.]]
+

Current revision

crystal structure of orotidine monophosphate decarboxylase mutant deltaR203A complexed with 6-azaUMP

PDB ID 1los

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools