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1lv2

From Proteopedia

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{{STRUCTURE_1lv2| PDB=1lv2 | SCENE= }}
 
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===Hepatocyte Nuclear Factor 4 is a Transcription Factor that Constitutively Binds Fatty Acids===
 
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{{ABSTRACT_PUBMED_12220494}}
 
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==Function==
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==Hepatocyte Nuclear Factor 4 is a Transcription Factor that Constitutively Binds Fatty Acids==
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[[http://www.uniprot.org/uniprot/HNF4G_HUMAN HNF4G_HUMAN]] Transcription factor. Has a lower transcription activation potential than HNF4-alpha.
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<StructureSection load='1lv2' size='340' side='right'caption='[[1lv2]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
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== Structural highlights ==
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==About this Structure==
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<table><tr><td colspan='2'>[[1lv2]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LV2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1LV2 FirstGlance]. <br>
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[[1lv2]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LV2 OCA].
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PLM:PALMITIC+ACID'>PLM</scene></td></tr>
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==Reference==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1lv2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1lv2 OCA], [https://pdbe.org/1lv2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1lv2 RCSB], [https://www.ebi.ac.uk/pdbsum/1lv2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1lv2 ProSAT]</span></td></tr>
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<ref group="xtra">PMID:012220494</ref><references group="xtra"/><references/>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/HNF4G_HUMAN HNF4G_HUMAN] Transcription factor. Has a lower transcription activation potential than HNF4-alpha.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/lv/1lv2_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1lv2 ConSurf].
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<div style="clear:both"></div>
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__TOC__
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Davis, R G.]]
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[[Category: Large Structures]]
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[[Category: Johnson, R.]]
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[[Category: Davis RG]]
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[[Category: Miller, A B.]]
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[[Category: Johnson R]]
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[[Category: Moore, J T.]]
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[[Category: Miller AB]]
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[[Category: Sefler, A.]]
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[[Category: Moore JT]]
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[[Category: Shearer, B.]]
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[[Category: Sefler A]]
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[[Category: Spitzer, T.]]
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[[Category: Shearer B]]
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[[Category: Williams, S P.]]
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[[Category: Spitzer T]]
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[[Category: Willson, T M.]]
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[[Category: Williams SP]]
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[[Category: Wisely, B.]]
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[[Category: Willson TM]]
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[[Category: Diabetes]]
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[[Category: Wisely B]]
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[[Category: Fatty acid]]
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[[Category: Hnf4]]
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[[Category: Mody]]
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[[Category: Nuclear receptor]]
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[[Category: Transcription]]
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[[Category: Transcription factor]]
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Current revision

Hepatocyte Nuclear Factor 4 is a Transcription Factor that Constitutively Binds Fatty Acids

PDB ID 1lv2

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