This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1m11

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
m (Protected "1m11" [edit=sysop:move=sysop])
Current revision (07:38, 14 February 2024) (edit) (undo)
 
(8 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:1m11.png|left|200px]]
 
-
{{STRUCTURE_1m11| PDB=1m11 | SCENE= }}
+
==structural model of human decay-accelerating factor bound to echovirus 7 from cryo-electron microscopy==
 +
<SX load='1m11' size='340' side='right' viewer='molstar' caption='[[1m11]], [[Resolution|resolution]] 16.00&Aring;' scene=''>
 +
== Structural highlights ==
 +
<table><tr><td colspan='2'>[[1m11]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Echovirus_E7 Echovirus E7] and [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1M11 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1M11 FirstGlance]. <br>
 +
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 16&#8491;</td></tr>
 +
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1m11 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1m11 OCA], [https://pdbe.org/1m11 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1m11 RCSB], [https://www.ebi.ac.uk/pdbsum/1m11 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1m11 ProSAT]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/DAF_HUMAN DAF_HUMAN] This protein recognizes C4b and C3b fragments that condense with cell-surface hydroxyl or amino groups when nascent C4b and C3b are locally generated during C4 and c3 activation. Interaction of daf with cell-associated C4b and C3b polypeptides interferes with their ability to catalyze the conversion of C2 and factor B to enzymatically active C2a and Bb and thereby prevents the formation of C4b2a and C3bBb, the amplification convertases of the complement cascade.<ref>PMID:7525274</ref>
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/m1/1m11_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1m11 ConSurf].
 +
<div style="clear:both"></div>
-
===structural model of human decay-accelerating factor bound to echovirus 7 from cryo-electron microscopy===
+
==See Also==
-
 
+
*[[CD55|CD55]]
-
{{ABSTRACT_PUBMED_12119400}}
+
*[[Virus coat proteins 3D structures|Virus coat proteins 3D structures]]
-
 
+
== References ==
-
==About this Structure==
+
<references/>
-
[[1m11]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Echovirus_e7 Echovirus e7] and [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1M11 OCA].
+
__TOC__
-
 
+
</SX>
-
==Reference==
+
[[Category: Echovirus E7]]
-
<ref group="xtra">PMID:012119400</ref><references group="xtra"/>
+
-
[[Category: Echovirus e7]]
+
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
-
[[Category: Baker, T S.]]
+
[[Category: Large Structures]]
-
[[Category: Bator, C M.]]
+
[[Category: Baker TS]]
-
[[Category: Chipman, P R.]]
+
[[Category: Bator CM]]
-
[[Category: He, Y.]]
+
[[Category: Chipman PR]]
-
[[Category: Kuhn, R J.]]
+
[[Category: He Y]]
-
[[Category: Lin, F.]]
+
[[Category: Kuhn RJ]]
-
[[Category: Medof, M E.]]
+
[[Category: Lin F]]
-
[[Category: Rossmann, M G.]]
+
[[Category: Medof ME]]
-
[[Category: Shoham, M.]]
+
[[Category: Rossmann MG]]
-
[[Category: Decay-accelerating factor]]
+
[[Category: Shoham M]]
-
[[Category: Icosahedral virus]]
+
-
[[Category: Scr]]
+
-
[[Category: Virus-receptor complex]]
+

Current revision

structural model of human decay-accelerating factor bound to echovirus 7 from cryo-electron microscopy

1m11, resolution 16.00Å

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1m11"
Personal tools