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1m2q

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[[Image:1m2q.png|left|200px]]
 
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{{STRUCTURE_1m2q| PDB=1m2q | SCENE= }}
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==Crystal structure of 1,8-di-hydroxy-4-nitro-xanten-9-one/CK2 kinase complex==
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<StructureSection load='1m2q' size='340' side='right'caption='[[1m2q]], [[Resolution|resolution]] 1.79&Aring;' scene=''>
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===Crystal structure of 1,8-di-hydroxy-4-nitro-xanten-9-one/CK2 kinase complex===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1m2q]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Zea_mays Zea mays]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1M2Q OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1M2Q FirstGlance]. <br>
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{{ABSTRACT_PUBMED_12419810}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.79&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MNX:1,8-DI-HYDROXY-4-NITRO-XANTHEN-9-ONE'>MNX</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1m2q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1m2q OCA], [https://pdbe.org/1m2q PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1m2q RCSB], [https://www.ebi.ac.uk/pdbsum/1m2q PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1m2q ProSAT]</span></td></tr>
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[[1m2q]] is a 1 chain structure of [[Casein kinase]] with sequence from [http://en.wikipedia.org/wiki/Zea_mays Zea mays]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1M2Q OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/CSK2A_MAIZE CSK2A_MAIZE] Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. The alpha chain contains the catalytic site.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/m2/1m2q_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1m2q ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Casein kinase|Casein kinase]]
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*[[Casein kinase 3D structures|Casein kinase 3D structures]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:012419810</ref><references group="xtra"/>
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[[Category: Large Structures]]
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[[Category: Non-specific serine/threonine protein kinase]]
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[[Category: Zea mays]]
[[Category: Zea mays]]
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[[Category: Battistutta, R.]]
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[[Category: Battistutta R]]
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[[Category: Moliner, E De.]]
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[[Category: De Moliner E]]
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[[Category: Moro, S.]]
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[[Category: Moro S]]
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[[Category: Pinna, L A.]]
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[[Category: Pinna LA]]
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[[Category: Sarno, S.]]
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[[Category: Sarno S]]
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[[Category: Zagotto, G.]]
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[[Category: Zagotto G]]
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[[Category: Zanotti, G.]]
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[[Category: Zanotti G]]
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[[Category: Inhibitor-enzyme complex]]
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[[Category: Kinase]]
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[[Category: Transferase]]
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Current revision

Crystal structure of 1,8-di-hydroxy-4-nitro-xanten-9-one/CK2 kinase complex

PDB ID 1m2q

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