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1m7g

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[[Image:1m7g.png|left|200px]]
 
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{{STRUCTURE_1m7g| PDB=1m7g | SCENE= }}
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==Crystal structure of APS kinase from Penicillium Chrysogenum: Ternary structure with ADP and APS==
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<StructureSection load='1m7g' size='340' side='right'caption='[[1m7g]], [[Resolution|resolution]] 1.43&Aring;' scene=''>
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===Crystal structure of APS kinase from Penicillium Chrysogenum: Ternary structure with ADP and APS===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1m7g]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Penicillium_chrysogenum Penicillium chrysogenum]. The August 2009 RCSB PDB [https://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Sulfotransferases'' by David Goodsell is [https://dx.doi.org/10.2210/rcsb_pdb/mom_2009_8 10.2210/rcsb_pdb/mom_2009_8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1M7G OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1M7G FirstGlance]. <br>
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{{ABSTRACT_PUBMED_12427029}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.43&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=ADX:ADENOSINE-5-PHOSPHOSULFATE'>ADX</scene>, <scene name='pdbligand=AV2:ADENOSINE-5-DIPHOSPHATE-2,3-VANADATE'>AV2</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1m7g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1m7g OCA], [https://pdbe.org/1m7g PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1m7g RCSB], [https://www.ebi.ac.uk/pdbsum/1m7g PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1m7g ProSAT]</span></td></tr>
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[[1m7g]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Penicillium_chrysogenum Penicillium chrysogenum]. The August 2009 RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Sulfotransferases'' by David Goodsell is [http://dx.doi.org/10.2210/rcsb_pdb/mom_2009_8 10.2210/rcsb_pdb/mom_2009_8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1M7G OCA].
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</table>
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== Function ==
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==Reference==
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[https://www.uniprot.org/uniprot/KAPS_PENCH KAPS_PENCH] Catalyzes the synthesis of activated sulfate.
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<ref group="xtra">PMID:012427029</ref><references group="xtra"/>
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== Evolutionary Conservation ==
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[[Category: Adenylyl-sulfate kinase]]
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/m7/1m7g_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1m7g ConSurf].
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<div style="clear:both"></div>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Penicillium chrysogenum]]
[[Category: Penicillium chrysogenum]]
[[Category: RCSB PDB Molecule of the Month]]
[[Category: RCSB PDB Molecule of the Month]]
[[Category: Sulfotransferases]]
[[Category: Sulfotransferases]]
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[[Category: Fisher, A J.]]
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[[Category: Fisher AJ]]
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[[Category: Lansdon, E B.]]
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[[Category: Lansdon EB]]
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[[Category: Segel, I H.]]
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[[Category: Segel IH]]
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[[Category: Adenylylsulfate kinase]]
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[[Category: Aps kinase]]
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[[Category: Nucleotide 2 kinase]]
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[[Category: Sulfate metabolism]]
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[[Category: Transferase]]
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Current revision

Crystal structure of APS kinase from Penicillium Chrysogenum: Ternary structure with ADP and APS

PDB ID 1m7g

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