1m7g
From Proteopedia
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- | {{Seed}} | ||
- | [[Image:1m7g.png|left|200px]] | ||
- | + | ==Crystal structure of APS kinase from Penicillium Chrysogenum: Ternary structure with ADP and APS== | |
- | + | <StructureSection load='1m7g' size='340' side='right'caption='[[1m7g]], [[Resolution|resolution]] 1.43Å' scene=''> | |
- | + | == Structural highlights == | |
- | + | <table><tr><td colspan='2'>[[1m7g]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Penicillium_chrysogenum Penicillium chrysogenum]. The August 2009 RCSB PDB [https://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Sulfotransferases'' by David Goodsell is [https://dx.doi.org/10.2210/rcsb_pdb/mom_2009_8 10.2210/rcsb_pdb/mom_2009_8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1M7G OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1M7G FirstGlance]. <br> | |
- | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.43Å</td></tr> | |
- | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=ADX:ADENOSINE-5-PHOSPHOSULFATE'>ADX</scene>, <scene name='pdbligand=AV2:ADENOSINE-5-DIPHOSPHATE-2,3-VANADATE'>AV2</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |
- | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1m7g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1m7g OCA], [https://pdbe.org/1m7g PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1m7g RCSB], [https://www.ebi.ac.uk/pdbsum/1m7g PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1m7g ProSAT]</span></td></tr> | |
- | + | </table> | |
- | + | == Function == | |
- | + | [https://www.uniprot.org/uniprot/KAPS_PENCH KAPS_PENCH] Catalyzes the synthesis of activated sulfate. | |
- | + | == Evolutionary Conservation == | |
- | < | + | [[Image:Consurf_key_small.gif|200px|right]] |
- | + | Check<jmol> | |
- | + | <jmolCheckbox> | |
- | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/m7/1m7g_consurf.spt"</scriptWhenChecked> | |
- | + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |
- | + | <text>to colour the structure by Evolutionary Conservation</text> | |
- | == | + | </jmolCheckbox> |
- | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1m7g ConSurf]. | |
- | + | <div style="clear:both"></div> | |
- | == | + | __TOC__ |
- | < | + | </StructureSection> |
- | [[ | + | [[Category: Large Structures]] |
[[Category: Penicillium chrysogenum]] | [[Category: Penicillium chrysogenum]] | ||
- | [[Category: | + | [[Category: RCSB PDB Molecule of the Month]] |
- | [[Category: | + | [[Category: Sulfotransferases]] |
- | [[Category: | + | [[Category: Fisher AJ]] |
- | [[Category: | + | [[Category: Lansdon EB]] |
- | [[Category: | + | [[Category: Segel IH]] |
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Current revision
Crystal structure of APS kinase from Penicillium Chrysogenum: Ternary structure with ADP and APS
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