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1mc1

From Proteopedia

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{{Seed}}
 
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[[Image:1mc1.png|left|200px]]
 
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<!--
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==BETA-LACTAM SYNTHETASE WITH PRODUCT (DGPC), AMP AND PPI==
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The line below this paragraph, containing "STRUCTURE_1mc1", creates the "Structure Box" on the page.
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<StructureSection load='1mc1' size='340' side='right'caption='[[1mc1]], [[Resolution|resolution]] 2.16&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1mc1]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_clavuligerus Streptomyces clavuligerus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MC1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1MC1 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.16&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AMP:ADENOSINE+MONOPHOSPHATE'>AMP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PCX:DEOXYGUANIDINOPROCLAVAMINIC+ACID'>PCX</scene>, <scene name='pdbligand=POP:PYROPHOSPHATE+2-'>POP</scene></td></tr>
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{{STRUCTURE_1mc1| PDB=1mc1 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1mc1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1mc1 OCA], [https://pdbe.org/1mc1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1mc1 RCSB], [https://www.ebi.ac.uk/pdbsum/1mc1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1mc1 ProSAT]</span></td></tr>
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</table>
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===BETA-LACTAM SYNTHETASE WITH PRODUCT (DGPC), AMP AND PPI===
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== Function ==
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[https://www.uniprot.org/uniprot/BLS_STRCL BLS_STRCL]
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== Evolutionary Conservation ==
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<!--
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[[Image:Consurf_key_small.gif|200px|right]]
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The line below this paragraph, {{ABSTRACT_PUBMED_12409610}}, adds the Publication Abstract to the page
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Check<jmol>
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(as it appears on PubMed at http://www.pubmed.gov), where 12409610 is the PubMed ID number.
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/mc/1mc1_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_12409610}}
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==About this Structure==
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</jmolCheckbox>
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1MC1 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Streptomyces_clavuligerus Streptomyces clavuligerus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MC1 OCA].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1mc1 ConSurf].
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<div style="clear:both"></div>
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==Reference==
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__TOC__
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The catalytic cycle of beta -lactam synthetase observed by x-ray crystallographic snapshots., Miller MT, Bachmann BO, Townsend CA, Rosenzweig AC, Proc Natl Acad Sci U S A. 2002 Nov 12;99(23):14752-7. Epub 2002 Oct 30. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12409610 12409610]
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</StructureSection>
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[[Category: Single protein]]
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[[Category: Large Structures]]
[[Category: Streptomyces clavuligerus]]
[[Category: Streptomyces clavuligerus]]
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[[Category: Bachmann, B O.]]
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[[Category: Bachmann BO]]
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[[Category: Miller, M T.]]
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[[Category: Miller MT]]
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[[Category: Rosenzweig, A C.]]
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[[Category: Rosenzweig AC]]
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[[Category: Townsend, C A.]]
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[[Category: Townsend CA]]
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[[Category: Asparagine synthetase]]
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[[Category: Beta-lactam synthetase]]
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[[Category: Carboxyethyl arginine]]
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[[Category: Clavulanic acid]]
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[[Category: Deoxyguanidinoproclavaminic acid]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 2 23:39:17 2008''
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Current revision

BETA-LACTAM SYNTHETASE WITH PRODUCT (DGPC), AMP AND PPI

PDB ID 1mc1

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