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1mix
From Proteopedia
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| - | [[Image:1mix.png|left|200px]] | ||
| - | + | ==Crystal structure of a FERM domain of Talin== | |
| - | + | <StructureSection load='1mix' size='340' side='right'caption='[[1mix]], [[Resolution|resolution]] 1.75Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[1mix]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MIX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1MIX FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.75Å</td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1mix FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1mix OCA], [https://pdbe.org/1mix PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1mix RCSB], [https://www.ebi.ac.uk/pdbsum/1mix PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1mix ProSAT]</span></td></tr> | |
| - | == | + | </table> |
| - | [[1mix]] is a 1 chain structure with sequence from [ | + | == Function == |
| + | [https://www.uniprot.org/uniprot/TLN1_CHICK TLN1_CHICK] Probably involved in connections of major cytoskeletal structures to the plasma membrane. Talin is a high molecular weight cytoskeletal protein concentrated at regions of cell-substratum contact and, in lymphocytes, at cell-cell contacts. | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/mi/1mix_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1mix ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
==See Also== | ==See Also== | ||
| - | *[[Talin|Talin]] | + | *[[Talin 3D structures|Talin 3D structures]] |
| - | + | __TOC__ | |
| - | + | </StructureSection> | |
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[[Category: Gallus gallus]] | [[Category: Gallus gallus]] | ||
| - | [[Category: Calderwood | + | [[Category: Large Structures]] |
| - | [[Category: Campbell | + | [[Category: Calderwood DA]] |
| - | [[Category: Critchley | + | [[Category: Campbell ID]] |
| - | [[Category: Garcia-Alvarez | + | [[Category: Critchley D]] |
| - | [[Category: Ginsberg | + | [[Category: Garcia-Alvarez B]] |
| - | [[Category: Liddington | + | [[Category: Ginsberg MH]] |
| - | + | [[Category: Liddington RC]] | |
| - | [[Category: Ulmer | + | [[Category: Ulmer TS]] |
| - | [[Category: | + | [[Category: De Pereda JM]] |
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Current revision
Crystal structure of a FERM domain of Talin
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