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1moj

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[[Image:1moj.png|left|200px]]
 
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{{STRUCTURE_1moj| PDB=1moj | SCENE= }}
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==Crystal structure of an archaeal dps-homologue from Halobacterium salinarum==
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<StructureSection load='1moj' size='340' side='right'caption='[[1moj]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
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===Crystal structure of an archaeal dps-homologue from Halobacterium salinarum===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1moj]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Halobacterium_salinarum Halobacterium salinarum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MOJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1MOJ FirstGlance]. <br>
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{{ABSTRACT_PUBMED_15365182}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1moj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1moj OCA], [https://pdbe.org/1moj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1moj RCSB], [https://www.ebi.ac.uk/pdbsum/1moj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1moj ProSAT]</span></td></tr>
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[[1moj]] is a 4 chain structure of [[Ferritin]] with sequence from [http://en.wikipedia.org/wiki/Halobacterium_salinarum Halobacterium salinarum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MOJ OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/DPS_HALSA DPS_HALSA] Protects DNA from oxidative damage by sequestering intracellular Fe(2+) ion and storing it in the form of Fe(3+) oxyhydroxide mineral. One hydrogen peroxide oxidizes two Fe(2+) ions, which prevents hydroxyl radical production by the Fenton reaction (By similarity).
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/mo/1moj_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1moj ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Ferritin|Ferritin]]
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*[[Ferritin 3D structures|Ferritin 3D structures]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:015365182</ref><ref group="xtra">PMID:016345079</ref><references group="xtra"/>
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[[Category: Halobacterium salinarum]]
[[Category: Halobacterium salinarum]]
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[[Category: Essen, L O.]]
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[[Category: Large Structures]]
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[[Category: Oesterhelt, D.]]
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[[Category: Essen LO]]
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[[Category: Offermann, S.]]
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[[Category: Oesterhelt D]]
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[[Category: Zeth, K.]]
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[[Category: Offermann S]]
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[[Category: Dna binding protein]]
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[[Category: Zeth K]]
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[[Category: Dp]]
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[[Category: Ferritin]]
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[[Category: Four-helix bundle]]
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[[Category: Halophilic]]
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Current revision

Crystal structure of an archaeal dps-homologue from Halobacterium salinarum

PDB ID 1moj

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