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1mtc

From Proteopedia

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{{Seed}}
 
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[[Image:1mtc.png|left|200px]]
 
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==GLUTATHIONE TRANSFERASE MUTANT Y115F==
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The line below this paragraph, containing "STRUCTURE_1mtc", creates the "Structure Box" on the page.
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<StructureSection load='1mtc' size='340' side='right'caption='[[1mtc]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1mtc]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MTC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1MTC FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GPR:(9R,10R)-9-(S-GLUTATHIONYL)-10-HYDROXY-9,10-DIHYDROPHENANTHRENE'>GPR</scene></td></tr>
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{{STRUCTURE_1mtc| PDB=1mtc | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1mtc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1mtc OCA], [https://pdbe.org/1mtc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1mtc RCSB], [https://www.ebi.ac.uk/pdbsum/1mtc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1mtc ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/GSTM1_RAT GSTM1_RAT] Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. The olfactory GST may be crucial for the acuity of the olfactory process.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/mt/1mtc_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1mtc ConSurf].
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<div style="clear:both"></div>
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===GLUTATHIONE TRANSFERASE MUTANT Y115F===
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==See Also==
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*[[Glutathione S-transferase 3D structures|Glutathione S-transferase 3D structures]]
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__TOC__
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<!--
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_12484753}}, adds the Publication Abstract to the page
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[[Category: Large Structures]]
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(as it appears on PubMed at http://www.pubmed.gov), where 12484753 is the PubMed ID number.
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{{ABSTRACT_PUBMED_12484753}}
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==About this Structure==
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1MTC is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MTC OCA].
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==Reference==
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Local protein dynamics and catalysis: detection of segmental motion associated with rate-limiting product release by a glutathione transferase., Codreanu SG, Ladner JE, Xiao G, Stourman NV, Hachey DL, Gilliland GL, Armstrong RN, Biochemistry. 2002 Dec 24;41(51):15161-72. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12484753 12484753]
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[[Category: Glutathione transferase]]
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[[Category: Rattus norvegicus]]
[[Category: Rattus norvegicus]]
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[[Category: Single protein]]
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[[Category: Armstrong RN]]
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[[Category: Armstrong, R N.]]
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[[Category: Gilliland GL]]
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[[Category: Gilliland, G L.]]
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[[Category: Ladner JE]]
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[[Category: Ladner, J E.]]
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[[Category: Xiao G]]
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[[Category: Xiao, G.]]
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[[Category: Glutathione transferase]]
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[[Category: Protein catalysis]]
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[[Category: Protein dynamic]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 05:04:02 2008''
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Current revision

GLUTATHIONE TRANSFERASE MUTANT Y115F

PDB ID 1mtc

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