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1mvk
From Proteopedia
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| - | [[Image:1mvk.png|left|200px]] | ||
| - | + | ==X-ray structure of the tetrameric mutant of the B1 domain of streptococcal protein G== | |
| + | <StructureSection load='1mvk' size='340' side='right'caption='[[1mvk]], [[Resolution|resolution]] 2.50Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[1mvk]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptococcus_sp._'group_G' Streptococcus sp. 'group G']. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MVK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1MVK FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1mvk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1mvk OCA], [https://pdbe.org/1mvk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1mvk RCSB], [https://www.ebi.ac.uk/pdbsum/1mvk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1mvk ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/SPG1_STRSG SPG1_STRSG] Binds to the constant Fc region of IgG with high affinity. | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/mv/1mvk_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1mvk ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| - | == | + | ==See Also== |
| - | + | *[[Protein G|Protein G]] | |
| - | + | __TOC__ | |
| - | + | </StructureSection> | |
| - | + | [[Category: Large Structures]] | |
| - | [[ | + | [[Category: Streptococcus sp. 'group G']] |
| - | + | [[Category: Dobrodumov A]] | |
| - | + | [[Category: Dyda F]] | |
| - | < | + | [[Category: Frank MK]] |
| - | [[Category: Streptococcus sp. 'group | + | [[Category: Gronenborn AM]] |
| - | [[Category: Dobrodumov | + | |
| - | [[Category: Dyda | + | |
| - | [[Category: Frank | + | |
| - | [[Category: Gronenborn | + | |
| - | + | ||
| - | + | ||
| - | + | ||
Current revision
X-ray structure of the tetrameric mutant of the B1 domain of streptococcal protein G
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