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1q6y

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[[Image:1q6y.gif|left|200px]]
[[Image:1q6y.gif|left|200px]]
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{{Structure
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<!--
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|PDB= 1q6y |SIZE=350|CAPTION= <scene name='initialview01'>1q6y</scene>, resolution 1.99&Aring;
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The line below this paragraph, containing "STRUCTURE_1q6y", creates the "Structure Box" on the page.
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|SITE=
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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|LIGAND= <scene name='pdbligand=COA:COENZYME+A'>COA</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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|ACTIVITY=
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or leave the SCENE parameter empty for the default display.
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|GENE= YFDW ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])
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-->
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|DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=PRK05398 PRK05398]</span>
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{{STRUCTURE_1q6y| PDB=1q6y | SCENE= }}
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|RELATEDENTRY=[[1pqy|1PQY]]
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1q6y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1q6y OCA], [http://www.ebi.ac.uk/pdbsum/1q6y PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1q6y RCSB]</span>
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}}
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'''Hypothetical protein YfdW from E. coli bound to Coenzyme A'''
'''Hypothetical protein YfdW from E. coli bound to Coenzyme A'''
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[[Category: NYSGXRC, New York Structural GenomiX Research Consortium.]]
[[Category: NYSGXRC, New York Structural GenomiX Research Consortium.]]
[[Category: Shapiro, L.]]
[[Category: Shapiro, L.]]
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[[Category: coenzyme some]]
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[[Category: Coenzyme some]]
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[[Category: intertwined dimer]]
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[[Category: Intertwined dimer]]
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[[Category: new york structural genomix research consortium]]
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[[Category: New york structural genomix research consortium]]
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[[Category: nysgxrc]]
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[[Category: Nysgxrc]]
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[[Category: protein structure initiative]]
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[[Category: Protein structure initiative]]
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[[Category: psi]]
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[[Category: Psi]]
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[[Category: structural genomic]]
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[[Category: Structural genomic]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 05:56:43 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 23:09:39 2008''
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Revision as of 02:56, 3 May 2008

Image:1q6y.gif

Template:STRUCTURE 1q6y

Hypothetical protein YfdW from E. coli bound to Coenzyme A


Overview

Crystal structures are reported for free and coenzyme A (CoA) bound forms of the YfdW protein from Escherichia coli, a representative type III CoA transferase. The structures reveal a two-domain protomer with interdomain connections forming a ring-like structure with a large central hole. Two protomers associate to form a highly intertwined dimer in which the hole of each ring is filled by the partner molecule. Each protomer binds a single CoA molecule and these CoA-binding sites are distant from one another in the dimer.

About this Structure

1Q6Y is a Single protein structure of sequence from Escherichia coli. Full crystallographic information is available from OCA.

Reference

Structure of Escherichia coli YfdW, a type III CoA transferase., Gogos A, Gorman J, Shapiro L, Acta Crystallogr D Biol Crystallogr. 2004 Mar;60(Pt 3):507-11. Epub 2004, Feb 25. PMID:14993676 Page seeded by OCA on Sat May 3 05:56:43 2008

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OCA

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