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1n0i

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{{Seed}}
 
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[[Image:1n0i.png|left|200px]]
 
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<!--
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==Crystal Structure of Ferrochelatase with Cadmium bound at active site==
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The line below this paragraph, containing "STRUCTURE_1n0i", creates the "Structure Box" on the page.
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<StructureSection load='1n0i' size='340' side='right'caption='[[1n0i]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1n0i]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1N0I OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1N0I FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CD:CADMIUM+ION'>CD</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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{{STRUCTURE_1n0i| PDB=1n0i | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1n0i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1n0i OCA], [https://pdbe.org/1n0i PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1n0i RCSB], [https://www.ebi.ac.uk/pdbsum/1n0i PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1n0i ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/CPFC_BACSU CPFC_BACSU] Involved in coproporphyrin-dependent heme b biosynthesis (PubMed:25646457, PubMed:25908396). Catalyzes the insertion of ferrous iron into coproporphyrin III to form Fe-coproporphyrin III (PubMed:25646457, PubMed:25908396). It can also insert iron into protoporphyrin IX (PubMed:1459957, PubMed:8119288, PubMed:21052751, PubMed:25646457). Has weaker activity with 2,4 disulfonate, deuteroporphyrin and 2,4 hydroxyethyl (PubMed:25646457, PubMed:12761666). In vitro, can also use Zn(2+) or Cu(2+) (PubMed:8119288, PubMed:16140324, PubMed:21052751, PubMed:12761666).<ref>PMID:12761666</ref> <ref>PMID:1459957</ref> <ref>PMID:16140324</ref> <ref>PMID:21052751</ref> <ref>PMID:25646457</ref> <ref>PMID:25826316</ref> <ref>PMID:25908396</ref> <ref>PMID:8119288</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/n0/1n0i_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1n0i ConSurf].
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<div style="clear:both"></div>
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===Crystal Structure of Ferrochelatase with Cadmium bound at active site===
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==See Also==
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*[[Ferrochelatase 3D structures|Ferrochelatase 3D structures]]
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== References ==
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<references/>
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The line below this paragraph, {{ABSTRACT_PUBMED_12761666}}, adds the Publication Abstract to the page
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__TOC__
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(as it appears on PubMed at http://www.pubmed.gov), where 12761666 is the PubMed ID number.
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</StructureSection>
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{{ABSTRACT_PUBMED_12761666}}
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==About this Structure==
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1N0I is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1N0I OCA].
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==Reference==
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<ref group="xtra">PMID:12761666</ref><references group="xtra"/>
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[[Category: Bacillus subtilis]]
[[Category: Bacillus subtilis]]
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[[Category: Ferrochelatase]]
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[[Category: Large Structures]]
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[[Category: Al-Karadaghi, S.]]
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[[Category: Al-Karadaghi S]]
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[[Category: Fodje, M N.]]
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[[Category: Fodje MN]]
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[[Category: Hansson, A.]]
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[[Category: Hansson A]]
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[[Category: Hansson, M.]]
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[[Category: Hansson M]]
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[[Category: Lecerof, D.]]
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[[Category: Lecerof D]]
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[[Category: Leon, R A.]]
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[[Category: Leon RA]]
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[[Category: Olsson, U.]]
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[[Category: Olsson U]]
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[[Category: Ryde, U.]]
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[[Category: Ryde U]]
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[[Category: Sigfridsson, E.]]
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[[Category: Sigfridsson E]]
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[[Category: Pi-helix]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 22:08:47 2009''
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Current revision

Crystal Structure of Ferrochelatase with Cadmium bound at active site

PDB ID 1n0i

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