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1n42

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[[Image:1n42.png|left|200px]]
 
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{{STRUCTURE_1n42| PDB=1n42 | SCENE= }}
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==Crystal Structure of Annexin V R149E Mutant==
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<StructureSection load='1n42' size='340' side='right'caption='[[1n42]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
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===Crystal Structure of Annexin V R149E Mutant===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1n42]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1N42 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1N42 FirstGlance]. <br>
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{{ABSTRACT_PUBMED_12401794}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1n42 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1n42 OCA], [https://pdbe.org/1n42 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1n42 RCSB], [https://www.ebi.ac.uk/pdbsum/1n42 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1n42 ProSAT]</span></td></tr>
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[[1n42]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1N42 OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/ANXA5_RAT ANXA5_RAT] This protein is an anticoagulant protein that acts as an indirect inhibitor of the thromboplastin-specific complex, which is involved in the blood coagulation cascade.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/n4/1n42_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1n42 ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
*[[Annexin|Annexin]]
*[[Annexin|Annexin]]
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*[[Annexin 3D structures|Annexin 3D structures]]
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==Reference==
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__TOC__
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<ref group="xtra">PMID:012401794</ref><references group="xtra"/>
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Rattus norvegicus]]
[[Category: Rattus norvegicus]]
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[[Category: Campos, B.]]
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[[Category: Campos B]]
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[[Category: Commodore, L.]]
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[[Category: Commodore L]]
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[[Category: Dedman, J R.]]
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[[Category: Dedman JR]]
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[[Category: Head, J F.]]
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[[Category: Head JF]]
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[[Category: Mealy, T R.]]
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[[Category: Mealy TR]]
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[[Category: Mo, Y D.]]
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[[Category: Mo YD]]
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[[Category: Seaton, B A.]]
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[[Category: Seaton BA]]
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[[Category: Lipid binding protein]]
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[[Category: Membrane binding protein]]
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[[Category: Phospholipid]]
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Current revision

Crystal Structure of Annexin V R149E Mutant

PDB ID 1n42

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