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1n55

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[[Image:1n55.png|left|200px]]
 
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{{STRUCTURE_1n55| PDB=1n55 | SCENE= }}
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==0.83A resolution structure of the E65Q mutant of Leishmania mexicana triosephosphate isomerase complexed with 2-phosphoglycolate==
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<StructureSection load='1n55' size='340' side='right'caption='[[1n55]], [[Resolution|resolution]] 0.83&Aring;' scene=''>
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===0.83A resolution structure of the E65Q mutant of Leishmania mexicana triosephosphate isomerase complexed with 2-phosphoglycolate===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1n55]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Leishmania_mexicana Leishmania mexicana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1N55 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1N55 FirstGlance]. <br>
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{{ABSTRACT_PUBMED_12522213}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 0.83&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACY:ACETIC+ACID'>ACY</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PGA:2-PHOSPHOGLYCOLIC+ACID'>PGA</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1n55 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1n55 OCA], [https://pdbe.org/1n55 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1n55 RCSB], [https://www.ebi.ac.uk/pdbsum/1n55 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1n55 ProSAT]</span></td></tr>
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[[1n55]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Leishmania_mexicana Leishmania mexicana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1N55 OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/TPIS_LEIME TPIS_LEIME]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/n5/1n55_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1n55 ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Triose Phosphate Isomerase|Triose Phosphate Isomerase]]
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*[[Triose phosphate isomerase 3D structures|Triose phosphate isomerase 3D structures]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:012522213</ref><ref group="xtra">PMID:018754631</ref><references group="xtra"/>
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[[Category: Large Structures]]
[[Category: Leishmania mexicana]]
[[Category: Leishmania mexicana]]
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[[Category: Triose-phosphate isomerase]]
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[[Category: Kursula I]]
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[[Category: Kursula, I.]]
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[[Category: Wierenga RK]]
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[[Category: Wierenga, R K.]]
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[[Category: Atomic resolution]]
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[[Category: Enzyme-ligand complex]]
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[[Category: Isomerase]]
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[[Category: Low-barrier hydrogen bond]]
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[[Category: Tim]]
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[[Category: Transition-state analogue]]
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Current revision

0.83A resolution structure of the E65Q mutant of Leishmania mexicana triosephosphate isomerase complexed with 2-phosphoglycolate

PDB ID 1n55

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