This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1nch

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (07:55, 14 February 2024) (edit) (undo)
 
(11 intermediate revisions not shown.)
Line 1: Line 1:
-
{{Seed}}
 
-
[[Image:1nch.png|left|200px]]
 
-
<!--
+
==STRUCTURAL BASIS OF CELL-CELL ADHESION BY CADHERINS==
-
The line below this paragraph, containing "STRUCTURE_1nch", creates the "Structure Box" on the page.
+
<StructureSection load='1nch' size='340' side='right'caption='[[1nch]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[1nch]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NCH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1NCH FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
-
-->
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=YB:YTTERBIUM+(III)+ION'>YB</scene></td></tr>
-
{{STRUCTURE_1nch| PDB=1nch | SCENE= }}
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1nch FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1nch OCA], [https://pdbe.org/1nch PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1nch RCSB], [https://www.ebi.ac.uk/pdbsum/1nch PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1nch ProSAT]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/CADH2_MOUSE CADH2_MOUSE] Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH2 may be involved in neuronal recognition mechanism. In hippocampal neurons, may regulate dendritic spine density.<ref>PMID:11433297</ref> <ref>PMID:17988630</ref>
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/nc/1nch_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1nch ConSurf].
 +
<div style="clear:both"></div>
-
===STRUCTURAL BASIS OF CELL-CELL ADHESION BY CADHERINS===
+
==See Also==
-
 
+
*[[Cadherin 3D structures|Cadherin 3D structures]]
-
 
+
== References ==
-
<!--
+
<references/>
-
The line below this paragraph, {{ABSTRACT_PUBMED_7885471}}, adds the Publication Abstract to the page
+
__TOC__
-
(as it appears on PubMed at http://www.pubmed.gov), where 7885471 is the PubMed ID number.
+
</StructureSection>
-
-->
+
[[Category: Large Structures]]
-
{{ABSTRACT_PUBMED_7885471}}
+
-
 
+
-
==About this Structure==
+
-
1NCH is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NCH OCA].
+
-
 
+
-
==Reference==
+
-
<ref group="xtra">PMID:7885471</ref><references group="xtra"/>
+
[[Category: Mus musculus]]
[[Category: Mus musculus]]
-
[[Category: Als-Nielsen, J.]]
+
[[Category: Als-Nielsen J]]
-
[[Category: Colman, D R.]]
+
[[Category: Colman DR]]
-
[[Category: Fannon, A M.]]
+
[[Category: Fannon AM]]
-
[[Category: Grubel, G.]]
+
[[Category: Grubel G]]
-
[[Category: Hendrickson, W A.]]
+
[[Category: Hendrickson WA]]
-
[[Category: Kwong, P D.]]
+
[[Category: Kwong PD]]
-
[[Category: Legrand, J F.]]
+
[[Category: Legrand J-F]]
-
[[Category: Lehmann, M S.]]
+
[[Category: Lehmann MS]]
-
[[Category: Shapiro, L.]]
+
[[Category: Shapiro L]]
-
[[Category: Thompson, A.]]
+
[[Category: Thompson A]]
-
[[Category: Cadherin]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 15:40:17 2009''
+

Current revision

STRUCTURAL BASIS OF CELL-CELL ADHESION BY CADHERINS

PDB ID 1nch

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1nch"
Personal tools